BDBM92927 Immucillins, 11

SMILES OC1CCN(Cc2c[nH]c3c2nc[nH]c3=O)C1

InChI Key InChIKey=GGDSFMWTCISSAD-UHFFFAOYSA-N

Data  1 Kd  2 ITC

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92927   

TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College of Medicine

LigandPNGBDBM92927(Immucillins, 11)
Show SMILES OC1CCN(Cc2c[nH]c3c2nc[nH]c3=O)C1
Show InChI InChI=1S/C11H12N4O2/c16-8-1-2-15(5-8)4-7-3-12-10-9(7)13-6-14-11(10)17/h3,6,8,16H,1-2,4-5H2
Affinity DataKd:  0.383nMAssay Description:Inhibition assay using human PNP.More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 92927   

CellPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College of Medicine

SyringePNGBDBM92927(Immucillins, 11)
ITC DataΔG°: -12.9kcal/mole
pH: 7.4 T: 25.00°C 
CellPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College of Medicine

SyringePNGBDBM92927(Immucillins, 11)
ITC DataΔH°: -12.8kcal/mole
pH: 7.4 T: 27.00°C