BDBM97430 50460, 14::BPH-1358
SMILES O=C(Nc1cccc(c1)C1=NCCN1)c1ccc(cc1)-c1ccc(cc1)C(=O)Nc1cccc(c1)C1=NCCN1
InChI Key InChIKey=HOYOJUMMRGKESB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 97430
Affinity DataIC50: 1.80E+3nMpH: 7.4 T: 2°CAssay Description:Human FPPS was expressed and purified and inhibition assays carried out as described previously.More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human FPPS pre-incubated for 30 mins using GPP and IPP by continuous spectrophotometric assayMore data for this Ligand-Target Pair
TargetTuberculosinyl adenosine transferase(Mycobacterium tuberculosis H37Rv)
University Of California San Diego
University Of California San Diego
Affinity DataIC50: 9.60E+4nMAssay Description:For inhibition assay of Rv3378c, using tuberculosinyl diphosphate and adenosine as substrates, a mixture of 100 µM TPP, 100 µM adenosine,75 µg/mL Rv3...More data for this Ligand-Target Pair