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Found 2157 Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1'
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505262(CHEMBL4559408)
Affinity DataKi:  2nMAssay Description:Inhibition of ROMK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50022784((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50171290(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50049750((S)-3-(azetidin-2-ylmethoxy)pyridine | 3-((S)-1-Az...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50133817(4-(3-Chloro-pyridin-2-yl)-piperazine-1-carboxylic ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50094703(5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM21280(5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)met...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456266(((R)-1-(5-(((2-hydroxy-2- (4-methyl-1-oxo-1,3- dih...)
Affinity DataIC50:  0.150nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2), 1 Mg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456266(((R)-1-(5-(((2-hydroxy-2- (4-methyl-1-oxo-1,3- dih...)
Affinity DataIC50:  0.570nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456149(US10723723, Example 35)
Affinity DataIC50:  1nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456226((R)-5'-(((2-hydroxy-2-(4- methyl-1-oxo-1,3- dihydr...)
Affinity DataIC50:  1.10nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2), 1 Mg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456268((R)-1-(5-(((2-hydroxy-2- (4-methyl-1-oxo-1,3- dihy...)
Affinity DataIC50:  2.10nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2), 1 Mg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456260((R)-6-(4-(((2-hydroxy-2- (4-methyl-1-oxo-1,3- dihy...)
Affinity DataIC50:  2.40nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM194954(US9206198, 7)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of rat Kir1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM195013(US9206198, 78 | US9206198, 79)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM265526(US9718808, 44)
Affinity DataIC50:  3.10nMAssay Description:A Thallium Flux Assay was performed on each of the final product compounds of the Examples. This assay has been described previously; see, e.g., PCT ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM265519(US9718808, 41)
Affinity DataIC50:  3.30nMAssay Description:A Thallium Flux Assay was performed on each of the final product compounds of the Examples. This assay has been described previously; see, e.g., PCT ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM266980(US9718808, 109)
Affinity DataIC50:  3.40nMAssay Description:A Thallium Flux Assay was performed on each of the final product compounds of the Examples. This assay has been described previously; see, e.g., PCT ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456264((R)-3-(difluoromethoxy)- 1-(5-(((2-hydroxy-2-(4- m...)
Affinity DataIC50:  3.60nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456268((R)-1-(5-(((2-hydroxy-2- (4-methyl-1-oxo-1,3- dihy...)
Affinity DataIC50:  3.60nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM363473((S)-9-(2-(6-(1H-tetrazol-1- yl)pyridin-3-yl)-2-hyd...)
Affinity DataIC50:  3.80nMAssay Description:Blocking of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM194951(US9206198, 5)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM194963(US9206198, 18)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM194967(US9206198, 22)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456277(6-(4-(((1-hydroxy-1-(4- methyl-1-oxo-1,3- dihydroi...)
Affinity DataIC50:  4nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50249205(CHEMBL4062753)
Affinity DataIC50:  4nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM194951(US9206198, 5)
Affinity DataIC50:  4nMAssay Description:Inhibition of human ROMK expressed in CHO cells by whole cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM265547(US9718808, 51)
Affinity DataIC50:  4.30nMAssay Description:A Thallium Flux Assay was performed on each of the final product compounds of the Examples. This assay has been described previously; see, e.g., PCT ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456141(US10723723, Example 7-I | US10723723, Example 7-II)
Affinity DataIC50:  4.70nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2), 1 Mg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM423209((R)-4-methyl-5-(4-((6- (4-methyl-1H-imidazol- 1-yl...)
Affinity DataIC50:  4.70nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM338554(US9751881, Example 83)
Affinity DataIC50:  4.70nMAssay Description:Assay Protocol: The ROMK channel functional thallium flux assay was performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM423206((R)-4-methoxy-6-(4- ((3-(4-methyl-1-oxo-1,3- dihyd...)
Affinity DataIC50:  4.80nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM363475(9-(2-(4-(1H-tetrazol-1- yl)phenyl)-2-hydroxyethyl)...)
Affinity DataIC50:  4.80nMAssay Description:Blocking of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM423204(US10501449, Example 23-I | US10501449, Example 255...)
Affinity DataIC50:  4.90nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50249244(CHEMBL4103004)
Affinity DataIC50:  5nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM194954(US9206198, 7)
Affinity DataIC50:  5nMAssay Description:Inhibition of human ROMK expressed in CHO cells by whole cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM423199(US10501449, Example 2-I)
Affinity DataIC50:  5.70nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM265571(US9718808, 59)
Affinity DataIC50:  6nMAssay Description:A Thallium Flux Assay was performed on each of the final product compounds of the Examples. This assay has been described previously; see, e.g., PCT ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM155921(US9018211, 2A)
Affinity DataIC50:  6nMAssay Description:Inhibition of ROMK (unknown origin) after 30 mins by Tl+ influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM350315(US10208064, Example 30)
Affinity DataIC50:  6nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM194970(US9206198, 25)
Affinity DataIC50:  6nMAssay Description:Inhibition of human ROMK expressed in CHO cells by whole cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM155921(US9018211, 2A)
Affinity DataIC50:  6nMAssay Description:Inhibition of ROMK (unknown origin) after 30 mins by Tl+ influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM350315(US10208064, Example 30)
Affinity DataIC50:  6nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456159((R)-6-(4-(((2-hydroxy-2- (4-methyl-1-oxo-1,3- dihy...)
Affinity DataIC50:  6.10nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2), 1 Mg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456278((R)-4-ethoxy-6-(4-(((2- hydroxy-2-(4-methyl-1- oxo...)
Affinity DataIC50:  6.20nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505266(CHEMBL4548110)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM456205((R)-1-(5-(((2-hydroxy-2- (4-methyl-1-oxo-1,3- dihy...)
Affinity DataIC50:  6.40nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM363474((R)-9-(2-hydroxy-2-(4-methyl-1- oxo-1,3-dihydroiso...)
Affinity DataIC50:  6.40nMAssay Description:Blocking of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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