Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase/G1/S-specific cyclin- 1'
TargetCyclin-dependent kinase/G1/S-specific cyclin- 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of CDK1/cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G1/S-specific cyclin- 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human CDK1/cyclinE using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G1/S-specific cyclin- 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human CDK1/cyclinE using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G1/S-specific cyclin- 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50263013(CHEMBL4079206)
Affinity DataIC50:  76nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G1/S-specific cyclin- 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50270298(CHEMBL4075720)
Affinity DataIC50:  96nMAssay Description:Inhibition of human CDK1/Cyclin E using RB protein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition measure after 120 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G1/S-specific cyclin- 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CDK1/cyclin E using RP protein as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed