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Found 356 Enz. Inhib. hit(s) with Target = 'Malonyl-CoA decarboxylase, mitochondrial'
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183286(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-N,...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183304(CHEMBL380487 | N-(2-cyanoethyl)-N-ethyl-4-(1,1,1,3...)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328246(3-(4-carbamoyl-1-(5-(1,1,1,3,3,3-hexafluoro-2-hydr...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328247(4-(3-carboxyphenyl)-1-(5-(1,1,1,3,3,3-hexafluoro-2...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183290(CHEMBL205506 | pyrrolidin-1-yl-[4-(2,2,2-trifluoro...)
Affinity DataIC50:  0.850nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328248(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328235(3-(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183294(CHEMBL204287 | piperidin-1-yl-[4-(2,2,2-trifluoro-...)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183287(CHEMBL202688 | N-benzyl-N-methyl-4-(2,2,2-trifluor...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328241(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183328(CHEMBL206852 | morpholin-4-yl-[4-(2,2,2-trifluoro-...)
Affinity DataIC50:  1.14nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328222(3-(4-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328244(4-(4-fluorophenyl)-1-(5-(1,1,1,3,3,3-hexafluoro-2-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183298(CHEMBL202689 | N-methoxy-N-methyl-4-(2,2,2-trifluo...)
Affinity DataIC50:  1.45nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328226(2-(2-(4-(3-(1H-tetrazol-5-yl)phenyl)piperazin-1-yl...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328245(1,1,1,3,3,3-hexafluoro-2-(2-(4-(2-fluorophenyl)-4-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328234(2-(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328237(3-(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183316(CHEMBL202746 | N-methyl-N-phenethyl-4-(2,2,2-trifl...)
Affinity DataIC50:  1.99nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328225(3-(4-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328227(3-(4-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183313(CHEMBL203835 | N-phenethyl-4-(2,2,2-trifluoro-1-hy...)
Affinity DataIC50:  2.65nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328221(2-(2-(4-(4-aminophenyl)piperazin-1-yl)thiazol-5-yl...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328238(3-(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328220(2-(2-(4-(3-aminophenyl)piperazin-1-yl)thiazol-5-yl...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328249(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328236(4-(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328239(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328243(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328242(1-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50190401(CHEMBL211177 | tert-butyl-(3S)-3-{[(5R)-5-(2,2,2-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of malonyl-coenzyme A decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50190407((3S)-3-methylpentan-3-yl 3-(5-(1,1,1,3,3,3-hexaflu...)
Affinity DataIC50:  5nMAssay Description:Inhibition of malonyl-coenzyme A decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328223(2-(4-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328254(1,1,1,3,3,3-hexafluoro-2-(2-(4-(trifluoromethyl)ph...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328250(4-(2-aminothiazol-4-yl)-7-(5-(1,1,1,3,3,3-hexafluo...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50190399(3-{[5-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of malonyl-coenzyme A decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50190397(CHEMBL208825 | tert-butyl-(3S)-3-{[5-(2,2,2-triflu...)
Affinity DataIC50:  7nMAssay Description:Inhibition of malonyl-coenzyme A decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183307(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50212235(CHEMBL400455 | N-(4-(1H-tetrazol-5-yl)butyl)-N-(4-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50212235(CHEMBL400455 | N-(4-(1H-tetrazol-5-yl)butyl)-N-(4-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50190410(CHEMBL378459 | tert-butyl-(3R)-3-{[(5R)-5-(2,2,2-t...)
Affinity DataIC50:  8nMAssay Description:Inhibition of malonyl-coenzyme A decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183307(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328212(1,1,1,3,3,3-hexafluoro-2-(2-(4-(4-fluorophenyl)pip...)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328211(1,1,1,3,3,3-hexafluoro-2-(2-(4-(3-fluorophenyl)pip...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328217(1,1,1,3,3,3-hexafluoro-2-(2-(4-(4-nitrophenyl)pipe...)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50190408(3-{[5-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of malonyl-coenzyme A decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50186046(CHEMBL210138 | N-(4-cyanobenzyl)-N-(5-(1,1,1,3,3,3...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50190413(CHEMBL379321 | tert-butyl-(3R)-3-{[5-(2,2,2-triflu...)
Affinity DataIC50:  10nMAssay Description:Inhibition of malonyl-coenzyme A decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50328213(2-(2-(4-(3,4-difluorophenyl)piperazin-1-yl)thiazol...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50186054(4-((3,5-dichloro-N-(5-(1,1,1,3,3,3-hexafluoro-2-hy...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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