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Found 297 Enz. Inhib. hit(s) with Target = 'Stromelysin-2'
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50259948(CHEMBL4096462)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human MMP10 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120222(US8691753, 71)
Affinity DataKi:  7.70nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM92441(RXP470, 1 | RXP470, Compound 4)
Affinity DataKi:  8nM ΔG°:  -46.2kJ/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM92441(RXP470, 1 | RXP470, Compound 4)
Affinity DataKi:  8.30nM ΔG°:  -46.1kJ/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using matrix metalloproteinases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120215(US8691753, 64)
Affinity DataKi:  35nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120160(US8691753, 8)
Affinity DataKi:  35nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120244(US8691753, 93)
Affinity DataKi:  38.8nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120157(US8691753, 5)
Affinity DataKi:  44nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120155(US8691753, 3)
Affinity DataKi:  47nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120158(US8691753, 6)
Affinity DataKi:  48nMAssay Description:Inhibition of human MMP-10 expressed in Escherichia coli BL21(DE3) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120164(US8691753, 12)
Affinity DataKi:  51nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM92448(Inhibitor, 18)
Affinity DataKi:  54nM ΔG°:  -41.5kJ/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120219(US8691753, 68)
Affinity DataKi:  71nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120212(US8691753, 61 | US8691753, 72)
Affinity DataKi:  76nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120258(US8691753, 95 bis)
Affinity DataKi:  80nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120162(US8691753, 10)
Affinity DataKi:  93nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120191(US8691753, 39)
Affinity DataKi:  99nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120213(US8691753, 62)
Affinity DataKi:  102nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120159(US8691753, 7)
Affinity DataKi:  111nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120168(US8691753, 16)
Affinity DataKi:  114nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120216(US8691753, 65)
Affinity DataKi:  119nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120156(US8691753, 4)
Affinity DataKi:  122nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120217(US8691753, 66)
Affinity DataKi:  130nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120241(US8691753, 90)
Affinity DataKi:  143nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50265078((4S)-5-amino-4-((2S)-2-((2S)-3-((4-bromophenyl)(hy...)
Affinity DataKi:  149nMAssay Description:Inhibition of human MMP10 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120243(US8691753, 92)
Affinity DataKi:  156nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120218(US8691753, 67)
Affinity DataKi:  168nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50182403((2R,3S)-N1-((S)-1-(3-phenoxybenzyl)-2-oxoazepan-3-...)
Affinity DataKi:  190nMAssay Description:Inhibition of MMP10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120170(US8691753, 18)
Affinity DataKi:  196nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50229322((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataKi:  240nMAssay Description:Binding affinity to MMP10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120173(US8691753, 21)
Affinity DataKi:  256nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120175(US8691753, 23)
Affinity DataKi:  276nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  299nM ΔG°:  -37.2kJ/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120256(US8691753, 106)
Affinity DataKi:  318nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50260826(CHEMBL497761 | N-hydroxy-2,3-bis(4-methoxyphenylsu...)
Affinity DataKi:  335nMAssay Description:Inhibition of human recombinant MMP10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM92449(Inhibitor, 19)
Affinity DataKi:  352nM ΔG°:  -36.8kJ/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120242(US8691753, 91)
Affinity DataKi:  353nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50260802(CHEMBL496717 | N-hydroxy-2,3-bis(phenylsulfonamido...)
Affinity DataKi:  356nMAssay Description:Inhibition of human recombinant MMP10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120231(US8691753, 80)
Affinity DataKi:  373nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120220(US8691753, 69)
Affinity DataKi:  382nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM92447(Inhibitor, 17)
Affinity DataKi:  390nM ΔG°:  -36.6kJ/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120221(US8691753, 70)
Affinity DataKi:  421nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120225(US8691753, 74)
Affinity DataKi:  430nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120203(US8691753, 52)
Affinity DataKi:  433nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120234(US8691753, 83)
Affinity DataKi:  435nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120190(US8691753, 38)
Affinity DataKi:  446nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120214(US8691753, 63)
Affinity DataKi:  447nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120158(US8691753, 6)
Affinity DataKi:  489nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120235(US8691753, 84)
Affinity DataKi:  514nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM120161(US8691753, 9)
Affinity DataKi:  520nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
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