Found 57 Enz. Inhib. hit(s) with Target = 'Na(+)/H(+) exchange regulatory cofactor NHE-RF1' TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1 [1-140](Homo sapiens (Human))
The University Of Queensland
The University Of Queensland
Affinity DataKi: 1.40E+3nM ΔG°: -33.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition assays were performed in FP buffer (DTT was avoided for Cys-PTHRct-9) containing fixed concentrations of both the fluorescently labeled p...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1 [133-300](Homo sapiens (Human))
The University Of Queensland
The University Of Queensland
Affinity DataKi: 7.00E+3nM ΔG°: -29.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition assays were performed in FP buffer (DTT was avoided for Cys-PTHRct-9) containing fixed concentrations of both the fluorescently labeled p...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1 [1-140](Homo sapiens (Human))
The University Of Queensland
The University Of Queensland
Affinity DataKi: 1.10E+4nM ΔG°: -28.1kJ/molepH: 7.4 T: 2°CAssay Description:Competition assays were performed in FP buffer (DTT was avoided for Cys-PTHRct-9) containing fixed concentrations of both the fluorescently labeled p...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1 [1-140](Homo sapiens (Human))
The University Of Queensland
The University Of Queensland
Affinity DataKi: 1.21E+5nM ΔG°: -22.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition assays were performed in FP buffer (DTT was avoided for Cys-PTHRct-9) containing fixed concentrations of both the fluorescently labeled p...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKd: 3.97E+3nMAssay Description:Binding affinity to NHERF1 PDZ1 domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence polarization based comp...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKd: 330nMAssay Description:Binding affinity to NHERF1 PDZ1 domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence polarization based comp...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKd: 1.64E+3nMAssay Description:Binding affinity to NHERF1 PDZ1 domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence polarization based comp...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1 [1-140](Homo sapiens (Human))
The University Of Queensland
The University Of Queensland
Affinity DataKd: 1.17E+4nMpH: 8.0 T: 2°CAssay Description:ITC measurements were conducted on a Microcal iTC200 (Malvern Instruments) in buffer consisting of 25 mM Tris (pH 8.0) and 100 mM NaCl. Proteins were...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1 [133-300](Homo sapiens (Human))
The University Of Queensland
The University Of Queensland
Affinity DataKd: 9.70E+3nMpH: 8.0 T: 2°CAssay Description:ITC measurements were conducted on a Microcal iTC200 (Malvern Instruments) in buffer consisting of 25 mM Tris (pH 8.0) and 100 mM NaCl. Proteins were...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKd: 780nMAssay Description:Binding affinity to NHERF1 PDZ1 domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence polarization based comp...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1 [1-140](Homo sapiens (Human))
The University Of Queensland
The University Of Queensland
Affinity DataKd: 1.60E+4nMpH: 7.4 T: 2°CAssay Description:SPR measurements were performed with a Biacore X100 instrument (GE Healthcare Life Sciences, Piscataway, NJ) at 15.0 °C. The biotinylated PTHRct-...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1 [133-300](Homo sapiens (Human))
The University Of Queensland
The University Of Queensland
Affinity DataKd: 1.15E+4nMpH: 7.4 T: 2°CAssay Description:SPR measurements were performed with a Biacore X100 instrument (GE Healthcare Life Sciences, Piscataway, NJ) at 15.0 °C. The biotinylated PTHRct-...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1 [133-300](Homo sapiens (Human))
The University Of Queensland
The University Of Queensland
Affinity DataKd: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:Competition assays were performed in FP buffer (DTT was avoided for Cys-PTHRct-9) containing fixed concentrations of both the fluorescently labeled p...More data for this Ligand-Target Pair
