Affinity DataKi: <1nM Kon: 1M-1s-1Assay Description:Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase), 1.5 ug/mL of colipase and 4 mM sodium taurodeoxycholatet (NaTDC) at a compou...More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Mixed type inhibition of porcine pancreatic lipase using 4MUO as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 220nM Kon: 220M-1s-1Assay Description:Tested for hydrolysis with 0.5 ug/mL of PPL (porcine pancreatic lipase), 1.5 ug/mL of colipase and 4 mM of sodium taurodeoxycholatet (NaTDC) at the c...More data for this Ligand-Target Pair
Affinity DataKi: 260nM ΔG°: -39.1kJ/mole IC50: 1.24E+3nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 710nM Kon: 710M-1s-1Assay Description:Tested for hydrolysis with 1.0 ug/mL of PPL (porcine pancreatic lipase), 2.2 ug/mL of colipase and 4 mM of sodium taurodeoxycholatet (NaTDC) at the c...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nM Kon: 1.10E+3M-1s-1Assay Description:Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase) at a compound dose of 0.2 gMore data for this Ligand-Target Pair
Affinity DataKi: 1.82E+3nM ΔG°: -34.1kJ/mole IC50: 8.77E+3nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 1.92E+3nM ΔG°: -33.9kJ/mole IC50: 9.12E+3nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nM Kon: 2.10E+3M-1s-1Assay Description:Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase) at the compound dose of 0.2 gMore data for this Ligand-Target Pair
Affinity DataKi: 2.17E+3nM ΔG°: -33.6kJ/mole IC50: 1.11E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 2.67E+3nM ΔG°: -33.1kJ/mole IC50: 1.27E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 2.75E+3nM ΔG°: -33.0kJ/mole IC50: 1.35E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 3.34E+3nM ΔG°: -32.5kJ/mole IC50: 1.64E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 4.96E+3nM ΔG°: -31.5kJ/mole IC50: 2.51E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 5.06E+3nM ΔG°: -31.4kJ/mole IC50: 2.54E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 5.70E+3nM Kon: 5.70E+3M-1s-1Assay Description:Tested for hydrolysis with 1.0 ug/mL of PPL (porcine pancreatic lipase)at the compound dose of 0.2 gMore data for this Ligand-Target Pair
Affinity DataKi: 6.28E+3nM ΔG°: -30.9kJ/mole IC50: 3.01E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 6.45E+3nM ΔG°: -30.8kJ/mole IC50: 2.92E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 6.79E+3nM ΔG°: -30.7kJ/mole IC50: 3.23E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 7.49E+3nM ΔG°: -30.4kJ/mole IC50: 3.48E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 8.57E+3nM ΔG°: -30.1kJ/mole IC50: 4.06E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 9.20E+3nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.28E+3nM ΔG°: -29.9kJ/mole IC50: 4.41E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 9.66E+3nM ΔG°: -29.8kJ/mole IC50: 4.57E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Competitive inhibition of porcine pancreatic lipase 4-nitrophenyl butyrate substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataKi: 1.44E+4nMAssay Description:Binding affinity to porcine pancreatic lipase using p-nitrophenyl butyrate as substrate by dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.75E+4nMAssay Description:Competitive inhibition of porcine pancreatic lipase 4-nitrophenyl butyrate substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataKi: 1.96E+4nMAssay Description:Competitive inhibition of porcine pancreatic lipase 4-nitrophenyl butyrate substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataKi: 2.16E+4nMAssay Description:Competitive inhibition of porcine pancreatic lipase 4-nitrophenyl butyrate substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.70E+4nMAssay Description:Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.10E+4nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+5nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+5nMAssay Description:Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+5nMAssay Description:Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.50E+5nMAssay Description:Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of porcine pancreatic lipase using p-NPB as substrate pretreated for 15 mins followed by substrate addition measured after 15 mins by spec...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human PL expressed in HEK293F cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of porcine pancreatic lipaseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 80.7nMAssay Description:Inhibition of pancreatic lipase assessed as umoles of oleic acic released per millimiter of triolein per hourMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair