Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN'
TargetPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 8.87E+3nMAssay Description:Inhibition of human PTEN using 3-O-Methylfluorescein phosphate as substrate incubated for 10 mins prior to substrate addition by fluorometryMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PTEN using 3-O-Methylfluorescein phosphate as substrate incubated for 10 mins prior to substrate addition by fluorometryMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human PTEN (1 to 403 residues) expressed in Escherichia coli strain BL21(DE3) using DiFMUP as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair