Found 5 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2 [2-188]/Protein Mdm4 [2-185]' TargetE3 ubiquitin-protein ligase Mdm2 [2-188]/Protein Mdm4 [2-185](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 1.45E+3nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2 [2-188]/Protein Mdm4 [2-185](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 1.51E+3nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2 [2-188]/Protein Mdm4 [2-185](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 2.13E+3nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2 [2-188]/Protein Mdm4 [2-185](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 1.40E+4nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2 [2-188]/Protein Mdm4 [2-185](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 1.67E+4nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
