KEGG   COMPOUND: C00575
Entry
C00575                      Compound                               
Name
3',5'-Cyclic AMP;
Cyclic adenylic acid;
Cyclic AMP;
Adenosine 3',5'-phosphate;
Adenosine 3',5'-cyclic phosphate;
cAMP
Formula
C10H12N5O6P
Exact mass
329.0525
Mol weight
329.2059
Structure
Reaction
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01522  Endocrine resistance
map02025  Biofilm formation - Pseudomonas aeruginosa
map02026  Biofilm formation - Escherichia coli
map04010  MAPK signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04072  Phospholipase D signaling pathway
map04111  Cell cycle - yeast
map04113  Meiosis - yeast
map04114  Oocyte meiosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04340  Hedgehog signaling pathway
map04361  Axon regeneration
map04371  Apelin signaling pathway
map04540  Gap junction
map04611  Platelet activation
map04670  Leukocyte transendothelial migration
map04710  Circadian rhythm
map04713  Circadian entrainment
map04714  Thermogenesis
map04720  Long-term potentiation
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04726  Serotonergic synapse
map04727  GABAergic synapse
map04728  Dopaminergic synapse
map04740  Olfactory transduction
map04742  Taste transduction
map04750  Inflammatory mediator regulation of TRP channels
map04910  Insulin signaling pathway
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04913  Ovarian steroidogenesis
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04919  Thyroid hormone signaling pathway
map04921  Oxytocin signaling pathway
map04922  Glucagon signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04924  Renin secretion
map04925  Aldosterone synthesis and secretion
map04926  Relaxin signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04960  Aldosterone-regulated sodium reabsorption
map04961  Endocrine and other factor-regulated calcium reabsorption
map04962  Vasopressin-regulated water reabsorption
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04976  Bile secretion
map05012  Parkinson disease
map05020  Prion disease
map05030  Cocaine addiction
map05031  Amphetamine addiction
map05032  Morphine addiction
map05034  Alcoholism
map05110  Vibrio cholerae infection
map05111  Biofilm formation - Vibrio cholerae
map05133  Pertussis
map05142  Chagas disease
map05146  Amoebiasis
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05414  Dilated cardiomyopathy
Network
nt06167  Human cytomegalovirus (HCMV)
nt06234  cAMP signaling (cancer)
nt06310  CRH-ACTH-cortisol signaling
nt06318  CaSR-PTH signaling
nt06322  TRH-TSH-TH signaling
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
nt06324  GHRH-GH-IGF signaling
nt06325  Hormone/cytokine signaling
nt06360  Cushing syndrome
nt06529  Thermogenesis
Enzyme
3.1.4.17        3.1.4.53        3.5.4.46        4.6.1.1
Brite
Compounds with biological roles [BR:br08001]
 Nucleic acids
  Cyclic nucleotides
   3',5'-Cyclic nuclcleotides
    C00575  3',5'-Cyclic AMP
Other DBs
CAS: 60-92-4
PubChem: 3854
ChEBI: 17489
KNApSAcK: C00001497
PDB-CCD: CMP[PDBj]
3DMET: B01289
NIKKAJI: J4.811I
KCF data

ATOM        22
            1   N4y N    26.7319  -14.6961
            2   C1y C    25.4512  -15.1095
            3   C8y C    27.7973  -15.4296
            4   C8x C    27.2093  -13.3048
            5   C1y C    25.0262  -16.3553
            6   O2x O    24.3160  -14.2595
            7   C8y C    29.0255  -14.5273
            8   N5x N    27.9312  -16.8444
            9   N5x N    28.6531  -13.3107
            10  C1y C    23.6464  -16.3553
            11  O1a O    25.6782  -17.4905
            12  C1y C    23.2215  -15.0513
            13  C8y C    30.2715  -15.0746
            14  C8x C    29.2469  -17.4322
            15  O2x O    22.6627  -17.3333
            16  C1x C    21.8942  -14.6147
            17  N5x N    30.4344  -16.5532
            18  N1a N    31.3717  -14.2538
            19  P1b P    21.1490  -16.9084
            20  O2x O    20.8579  -15.5461
            21  O1c O    21.1373  -18.3056
            22  O1c O    19.9323  -16.2098
BOND        25
            1     2   1 1 #Up
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    5  11 1 #Down
            11    6  12 1
            12    7  13 1
            13    8  14 2
            14   10  15 1 #Down
            15   12  16 1 #Up
            16   13  17 2
            17   13  18 1
            18   15  19 1
            19   16  20 1
            20   19  21 1
            21   19  22 2
            22    7   9 1
            23   10  12 1
            24   14  17 1
            25   19  20 1

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