| | COMPOUND: C15643 | |
Entry |
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Name |
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Formula |
C22H29FO5
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Exact mass |
392.1999
|
Mol weight |
392.4611
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Structure |
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Remark |
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Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AC Corticosteroids for local oral treatment
A01AC02 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA09 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AB Corticosteroids, moderately potent (group II)
D07AB19 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XB Corticosteroids, moderately potent, other combinations
D07XB05 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
D10 ANTI-ACNE PREPARATIONS
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AA Corticosteroids, combinations for treatment of acne
D10AA03 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB02 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD03 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA01 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01CB01 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
S02 OTOLOGICALS
S02B CORTICOSTEROIDS
S02BA Corticosteroids
S02BA06 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03B CORTICOSTEROIDS
S03BA Corticosteroids
S03BA01 Dexamethasone
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
Dexamethasone
D00292 Dexamethasone (JP18/USP/INN)
Inflammatory Bowel Disease Agents
Glucocorticoids
Dexamethasone
D00292 Dexamethasone (JP18/USP/INN)
Ophthalmic Agents
Ophthalmic Anti-inflammatories
Glucocorticoids, Ophthalmic
Dexamethasone
D00292 Dexamethasone (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1315 Ophthalmic cortisones
D00292 Dexamethasone (JP18/USP/INN)
2 Agents affecting individual organs
23 Digestive organ agents
239 Miscellaneous
2399 Others
D00292 Dexamethasone (JP18/USP/INN)
24 Hormones
245 Adrenal hormone preparations
2454 Fluorinated adrenocorticotropic hormones
D00292 Dexamethasone (JP18/USP/INN)
26 Epidermides
264 Analgesics, anti-itchings, astringents, anti-inflammatory agents
2646 Adrenocorticotropic hormones
D00292 Dexamethasone (JP18/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for integumentary system
57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
D00292 Dexamethasone (JP18/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Dexamethasone
D00292 Dexamethasone (JP18/USP/INN)
Second-class OTC drugs
Inorganic and organic chemicals
Dexamethasone
D00292 Dexamethasone (JP18/USP/INN)
Animal drugs in Japan [BR:br08331]
95 Agents for external use
953 Analgesics, anti-itchings, astringents and antiinflammatory agents
9539 Other analgesics, anti-itchings, astringents and inflammatory agents
C15643 Dexamethasone
96 Agents affecting metabolism
961 Hormone preparations (except agents for breeding and external use)
9612 Adrenal hormone preparations
C15643 Dexamethasone
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00011 Dexamethasone
D00292 Dexamethasone
Dermatological agent
DG03243 Atopic dermatitis agent
D00292 Dexamethasone
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00011 Dexamethasone
D00292 Dexamethasone
Metabolizing enzyme inducer
DG02853 CYP3A/CYP3A4 inducer
DG01635 CYP3A4 inducer
DG00011 Dexamethasone
D00292 Dexamethasone
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00292 Dexamethasone
Dermatological agent
DG03243 Atopic dermatitis agent
D00292 Dexamethasone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00292 Dexamethasone (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00292 Dexamethasone
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D00292
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00292
Topical steroids potency [br08317.html]
Classification in Japan
D00292
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Other DBs |
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KCF data |
ATOM 28
1 C2x C 15.4700 -16.9400
2 C5x C 15.4700 -18.3400
3 C2x C 16.6824 -19.0400
4 C2y C 17.8949 -18.3400
5 C1z C 17.8949 -16.9400
6 C2x C 16.6824 -16.2400
7 C1x C 19.1073 -19.0400
8 C1x C 20.3197 -18.3400
9 C1y C 20.3197 -16.9400
10 C1z C 19.1073 -16.2400
11 C1y C 21.5322 -16.2400
12 C1z C 21.5322 -14.8400
13 C1x C 20.3197 -14.1400
14 C1y C 19.1073 -14.8400
15 C1x C 23.9570 -16.2400
16 C1y C 23.9570 -14.8400
17 C1z C 22.7446 -14.1400
18 C5a C 22.7446 -12.2500
19 C1b C 23.9611 -11.5477
20 O5a O 21.5362 -11.5523
21 O1a O 25.1586 -12.2392
22 O1a O 23.7511 -13.1577
23 C1a C 25.1566 -14.1473
24 X F 19.1073 -17.6400
25 O5x O 14.2576 -19.0400
26 C1a C 21.5322 -13.4400
27 C1a C 17.8949 -15.5400
28 O1a O 18.1174 -13.8501
BOND 31
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 15 16 1
18 16 17 1
19 12 17 1
20 17 18 1
21 18 19 1
22 18 20 2
23 19 21 1
24 17 22 1 #Down
25 16 23 1 #Down
26 10 24 1 #Down
27 2 25 2
28 11 15 1
29 12 26 1 #Up
30 5 27 1 #Up
31 14 28 1 #Up
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