KEGG   COMPOUND: C07699
Entry
C07699                      Compound                               
Name
Nisoldipine
Formula
C20H24N2O6
Exact mass
388.1634
Mol weight
388.4144
Structure
Remark
Same as: D00618
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C08 CALCIUM CHANNEL BLOCKERS
   C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
    C08CA Dihydropyridine derivatives
     C08CA07 Nisoldipine
      D00618  Nisoldipine (JAN/USAN/INN) <US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Calcium Channel Blocking Agents, Dihydropyridines
   Nisoldipine
    D00618  Nisoldipine (JAN/USAN/INN)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01575  Calcium channel blocker
   DG01496  Calcium channel L type blocker
    D00618  Nisoldipine
  DG03231  Antihypertensive
   DG01928  Dihydropyridine calcium channel blocker
    D00618  Nisoldipine
 Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D00618  Nisoldipine
Drug classes [BR:br08332]
 Cardiovascular agent
  DG01928  Dihydropyridine calcium channel blocker
   D00618  Nisoldipine
  DG03231  Antihypertensive
   D00618  Nisoldipine
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Calcium channels
    CACNA1-L
     D00618  Nisoldipine (JAN/USAN/INN) <US>
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00618
Other DBs
CAS: 63675-72-9
PubChem: 9901
ChEBI: 7577 76917
NIKKAJI: J19.554E
KCF data

ATOM        28
            1   C1y C    23.9681  -15.8359
            2   C8y C    23.9564  -18.2346
            3   C2y C    25.1147  -15.1866
            4   C2y C    22.8213  -15.1866
            5   C8y C    22.8038  -18.8958
            6   C8x C    25.0972  -18.8958
            7   C2y C    25.1147  -13.8642
            8   C7a C    26.2614  -15.8359
            9   C2y C    22.8213  -13.8642
            10  C7a C    21.6862  -15.8359
            11  C8x C    22.8038  -20.2063
            12  N2b N    21.6805  -18.2346 #+
            13  C8x C    25.0972  -20.2063
            14  N1x N    23.9681  -13.2032
            15  C1a C    26.2614  -13.2032
            16  O7a O    27.3965  -15.1866
            17  O6a O    26.2614  -17.1640
            18  C1a C    21.6862  -13.2032
            19  O7a O    20.5454  -15.1866
            20  O6a O    21.6922  -17.0644
            21  C8x C    23.9564  -20.8790
            22  O3a O    23.1841  -17.2400
            23  O3a O    19.8142  -19.4749 #-
            24  C1b C    28.5314  -15.8359
            25  C1a C    19.4046  -15.8359
            26  C1c C    29.6664  -15.1806
            27  C1a C    30.8073  -15.8301
            28  C1a C    29.6605  -13.8642
BOND        29
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 2
            7     3   8 1
            8     4   9 2
            9     4  10 1
            10    5  11 2
            11    5  12 1
            12    6  13 1
            13    7  14 1
            14    7  15 1
            15    8  16 1
            16    8  17 2
            17    9  18 1
            18   10  19 1
            19   10  20 2
            20   11  21 1
            21   12  22 2
            22   12  23 1
            23   16  24 1
            24   19  25 1
            25   24  26 1
            26   26  27 1
            27   26  28 1
            28    9  14 1
            29   13  21 2

» Japanese version

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Drug (1)   
   KEGG DRUG (1)   
Chemical substance (5)   
   PubChem (1)   
   ChEBI (2)   
   HMDB (1)   
   NIKKAJI (1)   
All databases (6)   

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