KEGG   COMPOUND: C13826
Entry
C13826                      Compound                               
Name
Retigabine;
D-23129;
N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester
Formula
C16H18FN3O2
Exact mass
303.1383
Mol weight
303.3314
Structure
Remark
Same as: D09569
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AX Other antiepileptics
     N03AX21 Retigabine
      D09569  Ezogabine (USAN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG03199  Antiepileptic agent
   DG02037  GABA mimetic antiepileptic
    D09569  Ezogabine
 Transporter inhibitor
  DG01622  ABCB1 inhibitor
   D09569  Ezogabine
  DG02866  SLC22A8 inhibitor
   D09569  Ezogabine
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Potassium channels
    KCNQ
     D09569  Ezogabine (USAN)
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D09569
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D09569
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09569
Drug metabolizing enzymes and transporters [br08309.html]
 Drug transporters
  D09569
Other DBs
CAS: 150812-12-7
PubChem: 854071
ChEBI: 68584
PDB-CCD: FBX[PDBj]
NIKKAJI: J751.646K
KCF data

ATOM        22
            1   C8x C    29.6314  -20.0406
            2   C8y C    29.6314  -21.4402
            3   C8x C    30.8436  -22.1400
            4   C8x C    32.0556  -21.4402
            5   C8y C    32.0556  -20.0406
            6   C8x C    30.8436  -19.3408
            7   C1b C    33.2691  -19.3400
            8   N1b N    34.4825  -20.0406
            9   C8y C    35.6953  -19.3404
            10  C8x C    36.9083  -20.0408
            11  C8y C    38.1204  -19.3410
            12  C8y C    38.1204  -17.9414
            13  C8x C    36.9073  -17.2411
            14  C8x C    35.6953  -17.9408
            15  N1b N    39.3344  -17.2414
            16  C7a C    40.5464  -17.9412
            17  O7a O    41.7586  -17.2414
            18  C1b C    42.9706  -17.9412
            19  C1a C    44.1827  -17.2414
            20  O6a O    40.5464  -19.3408
            21  N1a N    39.3338  -20.0416
            22  X   F    28.4194  -22.1400
BOND        23
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14   13  14 2
            15    9  14 1
            16   12  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   16  20 2
            22   11  21 1
            23    2  22 1

» Japanese version

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Drug (1)   
   KEGG DRUG (1)   
Chemical substance (4)   
   PubChem (1)   
   ChEBI (1)   
   NIKKAJI (1)   
   PDB-CCD (1)   
All databases (5)   

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