| Entry |
|
|---|
| Name |
Tobramycin;
Nebramycin factor 6;
3'-Deoxykanamycin B
|
|---|
| Formula |
C18H37N5O9
|
|---|
| Exact mass |
467.2591
|
|---|
| Mol weight |
467.5145
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Reaction |
|
|---|
| Pathway |
| map00524 | Neomycin, kanamycin and gentamicin biosynthesis |
| map01110 | Biosynthesis of secondary metabolites |
|
|---|
| Enzyme |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01G AMINOGLYCOSIDE ANTIBACTERIALS
J01GB Other aminoglycosides
J01GB01 Tobramycin
D00063 Tobramycin (JP18/USP) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA12 Tobramycin
D00063 Tobramycin (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Aminoglycosides
Tobramycin
D00063 Tobramycin (JP18/USP)
Ophthalmic Agents
Ophthalmic Anti-Infectives
Antibacterials, Ophthalmic
Tobramycin
D00063 Tobramycin (JP18/USP)
Respiratory Tract/Pulmonary Agents
Cystic Fibrosis Agents
Inhaled Anti-infectives
Tobramycin
D00063 Tobramycin (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1317 Ophthalmic antibiotics
D00063 Tobramycin (JP18/USP)
6 Agents against pathologic organisms and parasites
61 Antibiotics
612 Acting mainly on gram-negative bacteria
6123 Amino sugars
D00063 Tobramycin (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01447 Aminoglycoside antibiotic
DG00608 Tobramycin
D00063 Tobramycin
Drug classes [BR:br08332]
Antibacterial
DG01447 Aminoglycoside antibiotic
D00063 Tobramycin
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Aminoglycoside
D00063 Tobramycin (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00063 Tobramycin
D00063 Tobramycin injection
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D00063
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00063
|
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| Other DBs |
|
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| KCF data |
ATOM 32
1 C1y C 20.6560 -20.0968
2 C1y C 20.6560 -21.4973
3 C1y C 21.8689 -22.1975
4 C1y C 23.0818 -21.4973
5 C1y C 23.0818 -20.0968
6 O2x O 21.8689 -19.3965
7 C1b C 19.4432 -19.3965
8 O1a O 18.2473 -20.0872
9 O1a O 19.4432 -22.1975
10 N1a N 21.8689 -23.5978
11 O1a O 24.3134 -22.2085
12 O2a O 24.3134 -19.3855
13 C1y C 25.4878 -18.6963
14 C1y C 26.7056 -19.3879
15 C1x C 27.9134 -18.6791
16 C1y C 27.9035 -17.2786
17 C1y C 26.6857 -16.5869
18 C1y C 25.4779 -17.2958
19 N1a N 26.7157 -20.7965
20 N1a N 29.0779 -16.5893
21 O1a O 24.2675 -16.6084
22 O2a O 26.6757 -15.1950
23 C1y C 27.8854 -14.4851
24 O2x O 29.0946 -15.1718
25 C1y C 30.3025 -14.4631
26 C1y C 30.2926 -13.0626
27 C1x C 29.0835 -12.3758
28 C1y C 27.8755 -13.0846
29 C1b C 31.5468 -15.1693
30 N1a N 31.5569 -16.5953
31 O1a O 31.5060 -12.3503
32 N1a N 26.6567 -12.3923
BOND 34
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1 #Up
8 7 8 1
9 2 9 1 #Down
10 3 10 1 #Up
11 4 11 1 #Down
12 5 12 1 #Down
13 13 12 1 #Down
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 13 18 1
20 14 19 1 #Up
21 16 20 1 #Up
22 18 21 1 #Up
23 17 22 1 #Down
24 23 22 1 #Down
25 23 24 1
26 24 25 1
27 25 26 1
28 26 27 1
29 27 28 1
30 23 28 1
31 25 29 1 #Up
32 29 30 1
33 26 31 1 #Down
34 28 32 1 #Down
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