3S3V: human dihydrofolate reductase Q35K/N64F double mutant binary complex with trimethoprim

PDB ID: 3S3VDownload
MMDB ID: 93893
PDB Deposition Date: 2011/5/18
Updated in MMDB: 2011/09
Experimental Method:
x-ray diffraction
Resolution: 1.53  Å
Source Organism:
Similar Structures:
Biological Unit for 3S3V: monomeric; determined by author
Molecular Components in 3S3V
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
(Gene symbol: DHFR)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
TRIMETHOPRIMTRIMETHOPRIM
2
5
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303