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1HWK:
COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH ATORVASTATIN
PDB ID:
1HWK
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MMDB ID:
16061
PDB Deposition Date:
2001/1/9
Updated in MMDB:
2021/11
Experimental Method:
x-ray diffraction
Resolution:
2.22 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1HWK: tetrameric; determined by author and by software (PISA)
Molecular Components in 1HWK
Label
Count
Molecule
Proteins (4 molecules)
A
B
C
D
4
Hmg-coa Reductase
(Gene symbol:
HMGCR
)
Chemicals and Non-standard biopolymers (9 molecules)
1
5
ADENOSINE-5'-DIPHOSPHATE
2
4
7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]- 3,5-DIHYDROXY-HEPTANOIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303