4J7X: Crystal structure of human sepiapterin reductase in complex with sulfasalazine

PDB ID: 4J7XDownload
MMDB ID: 117633
PDB Deposition Date: 2013/2/14
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 4J7X: dimeric; determined by author and by software (PISA)
Molecular Components in 4J7X
Label Count Molecule
Proteins (2 molecules)
2
Sepiapterin Reductase
(Gene symbol: SPR)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
7
SULFATE IONSULFATE ION
3
2
2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID
4
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303