4A03: Crystal Structure of Mycobacterium tuberculosis DXR in complex with the antibiotic FR900098 and cofactor NADPH

PDB ID: 4A03Download
MMDB ID: 96600
PDB Deposition Date: 2011/9/7
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 4A03: dimeric; determined by author and by software (PISA)
Molecular Components in 4A03
Label Count Molecule
Proteins (2 molecules)
2
1-deoxy-d-xylulose 5-phosphate Reductoisomerase
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
MANGANESE (II) IONMANGANESE (II) ION
2
2
3-[ethanoyl(hydroxy)amino]propylphosphonic acid3-[ethanoyl(hydroxy)amino]propylphosphonic acid
3
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303