3L2W: Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and GS9137 (Elvitegravir)

PDB ID: 3L2WDownload
MMDB ID: 80010
PDB Deposition Date: 2009/12/15
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3L2W: octameric; determined by author and by software (PISA)
Molecular Components in 3L2W
Label Count Molecule
Proteins (4 molecules)
4
Integrase
Molecule annotation
Nucleotides(4 molecules)
2
5'-d(*ap*tp*tp*gp*tp*cp*ap*tp*gp*gp*ap*ap*tp*tp*tp*tp*gp*tp*a)-3'
Molecule annotation
2
5'-d(*tp*ap*cp*ap*ap*ap*ap*tp*tp*cp*cp*ap*tp*gp*ap*cp*a)-3'
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
2
ZINC IONZINC ION
2
6
MANGANESE (II) IONMANGANESE (II) ION
3
2
AMMONIUM IONAMMONIUM ION
4
2
6-(3-chloro-2-fluorobenzyl)-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid6-(3-chloro-2-fluorobenzyl)-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
5
8
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303