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2WYJ:
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs
PDB ID:
2WYJ
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MMDB ID:
86538
PDB Deposition Date:
2009/11/16
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.38 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2WYJ: dimeric; determined by author and by software (PISA)
Molecular Components in 2WYJ
Label
Count
Molecule
Proteins (2 molecules)
A
1
Activated Factor XA Heavy Chain
(Gene symbol:
F10
)
B
1
Factor X Light Chain
(Gene symbol:
F10
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
(E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303