2XH1: Crystal structure of human KAT II-inhibitor complex

PDB ID: 2XH1Download
MMDB ID: 83592
PDB Deposition Date: 2010/6/8
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2XH1: dimeric; determined by software (PISA)
Molecular Components in 2XH1
Label Count Molecule
Proteins (2 molecules)
2
Kynurenine/alpha-aminoadipate Aminotransferase, Mitochondrial
(Gene symbol: AADAT)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
(3S)-10-(4-AMINOPIPERAZIN-1-YL)-9-FLUORO-7-HYDROXY-3-METHYL-2,3-DIHYDRO-8H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLATE(3S)-10-(4-AMINOPIPERAZIN-1-YL)-9-FLUORO-7-HYDROXY-3-METHYL-2,3-DIHYDRO-8H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLATE
2
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
3
1
IODIDE IONIODIDE ION
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303