3TCP: Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC569

PDB ID: 3TCPDownload
MMDB ID: 100658
PDB Deposition Date: 2011/8/9
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.69  Å
Source Organism:
Similar Structures:
Biological Unit for 3TCP: monomeric; determined by author
Molecular Components in 3TCP
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase MER
(Gene symbol: MERTK)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
1-[(trans-4-aminocyclohexyl)methyl]-N-butyl-3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine1-[(trans-4-aminocyclohexyl)methyl]-N-butyl-3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine
2
2
CHLORIDE IONCHLORIDE ION
3
2
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303