Highly selective and potent neuropeptide Y (NPY) Y1 receptor antagonists based on [Pro(30), Tyr(32), Leu(34)]NPY(28-36)-NH2 (BW1911U90)

J Med Chem. 2001 May 10;44(10):1479-82. doi: 10.1021/jm010031k.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cell Line
  • Cloning, Molecular
  • Cyclic AMP / biosynthesis
  • Eating / drug effects
  • Humans
  • Oligopeptides / chemical synthesis*
  • Oligopeptides / chemistry
  • Oligopeptides / metabolism
  • Oligopeptides / pharmacology
  • Rats
  • Receptors, Neuropeptide Y / metabolism*
  • Structure-Activity Relationship

Substances

  • BW 1991U90
  • Oligopeptides
  • Receptors, Neuropeptide Y
  • neuropeptide Y-Y1 receptor
  • neuropeptide Y2 receptor
  • neuropeptide Y5 receptor
  • neuropeptide Y4 receptor
  • Cyclic AMP