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  • 3VQP: hiv-1 in core domain in complex with 2,3-dihydro-1,4-benzodioxin-5- ylmethanol (10.1177/1087057112465979 )
  • 3VQQ: hiv-1 integrase core domain in complex with 2,1,3-benzothiadiazol-4- amine (10.1177/1087057112465979 )
  • 5U1C: structure of tetrameric hiv-1 strand transfer complex intasome (10.1126/SCIENCE.AAH5163 )
  • 6EB1: hiv-1 integrase catalytic core domain complexed with allosteric inhibitor (2s)-tert-butoxy[3-(3,4-dihydro-2h-1-benzopyran-6-yl)-1- phenylisoquinolin-4-yl]acetic acid (10.1021/ACSMEDCHEMLETT.8B00633 )
  • 6EB2: hiv-1 integrase catalytic core domain complexed with allosteric inhibitor (2s)-[1-(1-benzyl-1h-pyrazol-4-yl)-3-(3,4-dihydro-2h-1- benzopyran-6-yl)isoquinolin-4-yl](tert-butoxy)acetic acid (10.1021/ACSMEDCHEMLETT.8B00633 )
  • 6JCF: cryogenic structure of hiv-1 integrase catalytic core domain by synchrotron (10.3390/IJMS20081943 )
  • 6JCG: room temperature structure of hiv-1 integrase catalytic core domain by serial femtosecond crystallography. (10.3390/IJMS20081943 )
  • 6LMI: crystal structure of hiv-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-[3-(3,4-dihydro-2h-1-benzopyran-6-yl)-6- methanesulfonamido-2,3',4',5-tetramethyl-[1,1'-biphenyl]-4-yl]acetic acid (10.1016/J.BMC.2020.115643 )
  • 6LMQ: crystal structure of hiv-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-[3-(3,4-dihydro-2h-1,4-benzoxazin-6-yl)-6- methanesulfonamido-2,3',4',5-tetramethyl-[1,1'-biphenyl]-4-yl]acetic acid (10.1016/J.BMC.2020.115643 )
  • 6NCJ: structure of hiv-1 integrase with potent 5,6,7,8-tetrahydro-1,6- naphthyridine derivatives allosteric site inhibitors (10.1021/ACS.JMEDCHEM.8B01473 )
  • 6NUJ: hiv-1 integrase catalytic core domain complexed with allosteric inhibitor bi-224436 (10.7554/ELIFE.46344 )
  • 6PUT: structure of hiv cleaved synaptic complex (csc) intasome bound with calcium (10.1126/SCIENCE.AAY8015 )
  • 6PUW: structure of hiv cleaved synaptic complex (csc) intasome bound with magnesium and bictegravir (bic) (10.1126/SCIENCE.AAY8015 )
  • 6PUY: structure of hiv cleaved synaptic complex (csc) intasome bound with magnesium and insti xz426 (compound 4d) (10.1126/SCIENCE.AAY8015 )
  • 6PUZ: structure of hiv cleaved synaptic complex (csc) intasome bound with magnesium and insti xz446 (compound 4f) (10.1126/SCIENCE.AAY8015 )
  • 6T6E: crystal structure of the c-terminal domain of the hiv-1 integrase (pnl4-3) (10.1128/JVI.01035-20 )
  • 6T6I: crystal structure of the c-terminal domain of the hiv-1 integrase (subtype a2) (10.1128/JVI.01035-20 )
  • 6T6J: crystal structure of the c-terminal domain of the hiv-1 integrase (subtype a2, mutant n254k, k340q) (10.1128/JVI.01035-20 )
  • 6U8Q: cryoem structure of hiv-1 cleaved synaptic complex (csc) intasome (10.1016/J.JMB.2020.01.040 )
  • 6UM8: hiv integrase in complex with compound-14 (10.1021/ACS.JMEDCHEM.9B01681 )
  • 6V3K: structure of hiv cleaved synaptic complex (csc) intasome bound with magnesium and insti xz419 (compound 4c) (10.1126/SCIENCE.AAY8015 )
  • 6VDK: cryoem structure of hiv-1 conserved intasome core (10.1016/J.JMB.2020.01.040 )
  • 6VKA: hiv integrase core domain (in) in complex with dimer-spanning ligand
  • 6VLH: hiv integrase core domain (in) in complex with dimer-spanning ligand
  • 6VLM: core catalytic domain of hiv integrase in complex with virtual screening hit (10.1021/ACS.JCIM.0C00113 )
  • 6VQS: hiv integrase core domain (in) in complex with [5-(3-fluorophenyl)-1- benzofuran-3-yl]acetic acid
  • 6VRG: structure of hiv-1 integrase with native amino-terminal sequence (10.1186/S12977-020-00537-X )
  • 6VX2: hiv integrase core domain in complex with inhibitor (5-methyl-1- benzofuran-3-yl)acetic acid
  • 6W0U: hiv integrase core domain in complex with inhibitor 2-(2-ethynyl-5- methyl-1-benzofuran-3-yl)acetic acid
  • 6W42: hiv integrase core domain in complex with inhibitor 2-(5-methyl-2-(2- (thiophen-2-yl)ethynyl)-1-benzofuran-3-yl)acetic acid
  • 6WC8: hiv integrase core domain in complex with inhibitor 2-(5-(3- fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl) ethanoic acid
  • 6WE7: hiv integrase core domain in complex with inhibitor 3-methyl-2-{5- methyl-2-[2-(thiophen-2-yl)ethynyl]-1- benzofuran-3-yl}butanoic acid
  • 7D83: crystal structure of hiv-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-(2-(3-cyclohexylureido)-3,6-dimethyl-5-(5- methylchroman-6-yl)pyridin-4-yl)acetic acid (10.1016/J.BMCL.2020.127742 )
  • 7KE0: hiv-1 integrase catalytic core domain complexed with allosteric inhibitor stp03-0404
  • 7L1P: hiv integrase core domain (in) in complex with dimer-spanning ligand
  • 7L23: hiv integrase core domain in complex with inhibitor 2-(5-(3- fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl) ethanoic acid
  • 7LQP: rapid development of potent inhibitors of the hiv integrase-ledgf interaction by fragment-linking using off-rate screening
  • 7T9H: hiv integrase in complex with compound-15 (10.1021/ACS.JMEDCHEM.1C02169 )
  • 7T9O: hiv integrase in complex with compound-25 (10.1021/ACS.JMEDCHEM.1C02169 )