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  • 1DLO: human immunodeficiency virus type 1 (10.1016/S0969-2126(96)00091-3 )
  • 1EET: hiv-1 reverse transcriptase in complex with the inhibitor msc204 (10.1021/JM990572Y )
  • 1HAR: 2.2 angstroms resolution structure of the amino-terminal half of hiv-1 reverse transcriptase (fingers and palm subdomains) (10.1016/S0969-2126(94)00097-2 )
  • 1HNI: structure of hiv-1 reverse transcriptase in a complex with the nonnucleoside inhibitor alpha-apa r 95845 at 2.8 angstroms resolution (10.1016/S0969-2126(01)00168-X )
  • 1HNV: structure of hiv-1 rt(slash)tibo r 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors (10.1038/NSB0595-407 )
  • 1HPZ: human immunodeficiency virus type 1 (10.1006/JMBI.2001.4648 )
  • 1HQE: human immunodeficiency virus type 1 (10.1006/JMBI.2001.4648 )
  • 1HQU: human immunodeficiency virus type 1 (10.1006/JMBI.2001.4648 )
  • 1HYS: crystal structure of hiv-1 reverse transcriptase in complex with a polypurine tract rna:dna (10.1093/EMBOJ/20.6.1449 )
  • 1IKV: k103n mutant hiv-1 reverse transcriptase in complex with efivarenz (10.1046/J.1432-1327.2002.02811.X )
  • 1IKW: wild type hiv-1 reverse transcriptase in complex with efavirenz (10.1046/J.1432-1327.2002.02811.X )
  • 1IKX: k103n mutant hiv-1 reverse transcriptase in complex with the inhibitor pnu142721 (10.1046/J.1432-1327.2002.02811.X )
  • 1IKY: hiv-1 reverse transcriptase in complex with the inhibitor msc194 (10.1046/J.1432-1327.2002.02811.X )
  • 1J5O: crystal structure of met184ile mutant of hiv-1 reverse transcriptase in complex with double stranded dna template- primer (10.1073/PNAS.96.18.10027 )
  • 1QE1: crystal structure of 3tc-resistant m184i mutant of hiv-1 reverse transcriptase (10.1073/PNAS.96.18.10027 )
  • 1SV5: crystal structure of k103n mutant hiv-1 reverse transcriptase (rt) in complex with janssen-r165335 (10.1021/JM030558S )
  • 1TVR: hiv-1 rt/9-cl tibo (10.1006/JMBI.1996.0698 )
  • 1UWB: tyr 181 cys hiv-1 rt/8-cl tibo (10.1006/JMBI.1996.0698 )
  • 2VG5: crystal structures of hiv-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors (10.1016/J.BBRC.2007.11.036 )
  • 2VG6: crystal structures of hiv-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors (10.1016/J.BBRC.2007.11.036 )
  • 2VG7: crystal structures of hiv-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors (10.1016/J.BBRC.2007.11.036 )
  • 2YKM: crystal structure of hiv-1 reverse transcriptase (rt) in complex with a difluoromethylbenzoxazole (dfmb) pyrimidine thioether derivative, a non-nucleoside rt inhibitor (nnrti) (10.1021/JM200766B )
  • 2YKN: crystal structure of hiv-1 reverse transcriptase (rt) in complex with a difluoromethylbenzoxazole (dfmb) pyrimidine thioether derivative, a non-nucleoside rt inhibitor (nnrti) (10.1021/JM200766B )
  • 2ZD1: crystal structure of hiv-1 reverse transcriptase (rt) in complex with tmc278 (rilpivirine), a non-nucleoside rt inhibitor (10.1073/PNAS.0711209105 )
  • 2ZE2: crystal structure of l100i/k103n mutant hiv-1 reverse transcriptase (rt) in complex with tmc278 (rilpivirine), a non-nucleoside rt inhibitor (10.1073/PNAS.0711209105 )
  • 3BGR: crystal structure of k103n/y181c mutant hiv-1 reverse transcriptase (rt) in complex with tmc278 (rilpivirine), a non-nucleoside rt inhibitor (10.1073/PNAS.0711209105 )
  • 3HVT: structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer (10.1073/PNAS.91.9.3911 )
  • 3IG1: hiv-1 reverse transcriptase with the inhibitor beta-thujaplicinol bound at the rnase h active site (10.1016/J.STR.2009.09.016 )
  • 3IRX: crystal structure of hiv-1 reverse transcriptase (rt) in complex with the non-nucleoside rt inhibitor (e)-s-methyl 5-(1-(3,7-dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-5- (5-methyl-1,3,4-oxadiazol-2-yl)pent-1-enyl)-2-methoxy-3- methylbenzothioate. (10.1021/JM901167T )
  • 3IS9: crystal structure of the hiv-1 reverse transcriptase (rt) in complex with the alkenyldiarylmethane (adam) non-nucleoside rt inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1- diyl)bis(5-cyano-6-methoxybenzoate). (10.1021/JM901167T )
  • 3ISN: crystal structure of hiv-1 rt bound to a 6-vinylpyrimidine inhibitor (10.1002/ANIE.200905651 )
  • 3ITH: crystal structure of the hiv-1 reverse transcriptase bound to a 6-vinylpyrimidine inhibitor (10.1002/ANIE.200905651 )
  • 3KLE: crystal structure of azt-resistant hiv-1 reverse transcriptase crosslinked to a dsdna with a bound excision product, aztppppa (10.1038/NSMB.1908 )
  • 3KLG: crystal structure of azt-resistant hiv-1 reverse transcriptase crosslinked to pre-translocation aztmp-terminated dna (complex n) (10.1038/NSMB.1908 )
  • 3KLH: crystal structure of azt-resistant hiv-1 reverse transcriptase crosslinked to post-translocation aztmp-terminated dna (complex p) (10.1038/NSMB.1908 )
  • 3KLI: crystal structure of unliganded azt-resistant hiv-1 reverse transcriptase (10.1038/NSMB.1908 )
  • 3QO9: crystal structure of hiv-1 reverse transcriptase (rt) in complex with tsao-t, a non-nucleoside rt inhibitor (nnrti) (10.1021/JM101536X )
  • 3V4I: crystal structure of hiv-1 reverse transcriptase (rt) with dna and azttp (10.1038/NSMB.2223 )
  • 3V6D: crystal structure of hiv-1 reverse transcriptase (rt) cross-linked with azt-terminated dna (10.1038/NSMB.2223 )
  • 3V81: crystal structure of hiv-1 reverse transcriptase (rt) with dna and the nonnucleoside inhibitor nevirapine (10.1038/NSMB.2223 )
  • 4DG1: crystal structure of hiv-1 reverse transcriptase (rt) with polymorphism mutation k172a and k173a (10.1074/JBC.M112.351551 )
  • 4G1Q: crystal structure of hiv-1 reverse transcriptase (rt) in complex with rilpivirine (tmc278, edurant), a non-nucleoside rt-inhibiting drug (10.1038/NCHEM.1559 )
  • 4H4M: crystal structure of hiv-1 reverse transcriptase in complex with (e)- 3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)- yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj494), a non-nucleoside inhibitor (10.1021/JA3092642 )
  • 4H4O: crystal structure of hiv-1 reverse transcriptase (rt) in complex with (e)-3-(3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)- 4- fluorophenoxy)-5-fluorophenyl)acrylonitrile (jlj506), a non- nucleoside inhibitor (10.1021/JA3092642 )
  • 4I2P: crystal structure of hiv-1 reverse transcriptase in complex with rilpivirine (tmc278) based analogue (10.1186/1742-4690-9-99 )
  • 4I2Q: crystal structure of k103n/y181c mutant of hiv-1 reverse transcriptase in complex with rilpivirine (tmc278) analogue (10.1186/1742-4690-9-99 )
  • 4ICL: hiv-1 reverse transcriptase with bound fragment at the incoming dntp binding site (10.1021/JM301271J )
  • 4ID5: hiv-1 reverse transcriptase with bound fragment at the rnase h primer grip site (10.1021/JM301271J )
  • 4IDK: hiv-1 reverse transcriptase with bound fragment at the 428 site (10.1021/JM301271J )
  • 4IFV: detecting allosteric sites of hiv-1 reverse transcriptase by x-ray crystallographic fragment screening (10.1021/JM301271J )
  • 4IFY: hiv-1 reverse transcriptase with bound fragment at the knuckles site (10.1021/JM301271J )
  • 4IG0: hiv-1 reverse transcriptase with bound fragment at the 507 site (10.1021/JM301271J )
  • 4IG3: hiv-1 reverse transcriptase with bound fragment near knuckles site (10.1021/JM301271J )
  • 4KFB: hiv-1 reverse transcriptase with bound fragment at nnrti adjacent site (10.1021/JM301271J )
  • 4KKO: crystal structure of hiv-1 reverse transcriptase in complex with 4- ((4-methoxy-6-(2-morpholinoethoxy)-1,3,5-triazin-2-yl)amino)-2-((3- methylbut-2-en-1-yl)oxy)benzonitrile (jlj513), a non-nucleoside inhibitor (10.1016/J.BMCL.2013.06.093 )
  • 4KO0: crystal structure of hiv-1 reverse transcriptase (rt) in complex with an anilinylpyrimidine derivative (jlj-135) (10.1016/J.BMCL.2013.06.093 )
  • 4KSE: crystal structure of a hiv p51 (219-230) deletion mutant (10.1093/NAR/GKU143 )
  • 4LSL: crystal structure of hiv-1 reverse transcriptase in complex with (e)- 3-(3-(4-chloro-2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy) phenoxy)phenyl)acrylonitrile (jlj476), a non-nucleoside inhibitor (10.1111/CBDD.12266 )
  • 4LSN: crystal structure of hiv-1 reverse transcriptase in complex with (e)- 3-(3-bromo-5-(4-chloro-2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)- yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj518), a non-nucleoside inhibitor (10.1111/CBDD.12266 )
  • 4MFB: crystal structure of hiv-1 reverse transcriptase in complex with 8-(2- (2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy) indolizine-2-carbonitrile (jlj555), a non-nucleoside inhibitor (10.1021/JA408917N )
  • 4O44: crystal structure of hiv-1 reverse transcriptase in complex with 4- ((4-(mesitylamino)-6-(3-morpholinopropoxy)-1,3,5-triazin-2-yl)amino) benzonitrile (jlj529), a non-nucleoside inhibitor (10.1016/J.BBAGEN.2014.04.001 )
  • 4O4G: crystal structure of hiv-1 reverse transcriptase in complex with 4- ((4-(mesitylamino)-1,3,5-triazin-2-yl)amino)benzonitrile (jlj527), a non-nucleoside inhibitor (10.1016/J.BBAGEN.2014.04.001 )
  • 4PQU: crystal structure of hiv-1 reverse transcriptase in complex with rna/dna and datp (10.1093/NAR/GKU487 )
  • 4PUO: crystal structure of hiv-1 reverse transcriptase in complex with rna/dna and nevirapine (10.1093/NAR/GKU487 )
  • 4PWD: crystal structure of hiv-1 reverse transcriptase in complex with bulge-rna/dna and nevirapine (10.1093/NAR/GKU487 )
  • 4Q0B: crystal structure of hiv-1 reverse transcriptase in complex with gap- rna/dna and nevirapine (10.1093/NAR/GKU487 )
  • 4R5P: crystal structure of hiv-1 reverse transcriptase (rt) with dna and a nucleoside triphosphate mimic alpha-carboxy nucleoside phosphonate inhibitor (10.1073/PNAS.1420233112 )
  • 4RW4: crystal structure of hiv-1 reverse transcriptase (k103n,y181c) variant in complex with (e)-3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj494), a non-nucleoside inhibitor (10.1021/JM501908A )
  • 4RW6: crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with (e)-3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj494), a non-nucleoside inhibitor (10.1021/JM501908A )
  • 4RW7: crystal structure of hiv-1 reverse transcriptase (k103n, y181c) variant in complex with (e)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj532), a non-nucleoside inhibitor (10.1021/JM501908A )
  • 4RW8: crystal structure of hiv-1 reverse transcriptase in complex with (e)- 3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy) phenoxy)phenyl)acrylonitrile (jlj532), a non-nucleoside inhibitor' (10.1021/JM501908A )
  • 4RW9: crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with (e)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin- 1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj532), a non- nucleoside inhibitor (10.1021/JM501908A )
  • 4WE1: crystal structure of hiv-1 reverse transcriptase in complex with 5-(2- (2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-2- naphthonitrile (jlj600) (10.1021/ML5003713 )
  • 4ZHR: structure of hiv-1 rt q151m mutant (10.1107/S2053230X15017896 )
  • 5C24: crystal structure of hiv-1 reverse transcriptase in complex with 7- ((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-6,8- dimethylindolizine-2-carbonitrile (jlj605), a non-nucleoside inhibitor (10.1016/J.BMCL.2015.06.074 )
  • 5C25: crystal structure of hiv-1 reverse transcriptase in complex with 6- ((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-5,7-dimethyl-2- naphthonitrile (jlj639), a non-nucleoside inhibitor (10.1016/J.BMCL.2015.06.074 )
  • 5C42: crystal structure of hiv-1 reverse transcriptase (k101p) variant in complex with 8-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl) ethoxy)phenoxy)indolizine-2-carbonitrile (jlj555), a non-nucleoside inhibitor (10.1021/ACSMEDCHEMLETT.5B00254 )
  • 5CYM: hiv-1 reverse transcriptase complexed with 4-iodopyrazole (10.1107/S2052252515021259 )
  • 5CYQ: hiv-1 reverse transcriptase complexed with 4-bromopyrazole (10.1107/S2052252515021259 )
  • 5HBM: crystal structure of a dihydroxycoumarin rnase h active-site inhibitor in complex with hiv-1 reverse transcriptase
  • 5J1E: crystal structure of a hydroxypyridone carboxylic acid active-site rnase h inhibitor in complex with hiv reverse transcriptase (10.1021/ACS.JMEDCHEM.6B00465 )
  • 5T82: hiv-1 reverse transcriptase thumb subdomain (10.1007/S10858-016-0077-2 )
  • 5TER: crystal structure of hiv-1 reverse transcriptase in complex with 5- chloro-7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy) phenoxy)-8-methyl-2-naphthonitrile (jlj651), a non-nucleoside inhibitor (10.1021/ACSMEDCHEMLETT.6B00390 )
  • 5TUQ: crystal structure of a 6-cyclohexylmethyl-3-hydroxypyrimidine-2,4- dione inhibitor in complex with hiv reverse transcriptase (10.1016/J.EJMECH.2017.01.041 )
  • 5TW3: crystal structure of hiv-1 reverse transcriptase in complex with 5-(2- (2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)-4-fluorophenoxy)- 7-fluoro-2-naphthonitrile (jlj636), a non-nucleoside inhibitor (10.1124/MOL.116.107755 )
  • 5TXM: structure of hiv-1 reverse transcriptase (rt) ternary complex with a double stranded dna and an incoming ddatp (10.1128/AAC.00224-17 )
  • 5TXN: structure of q151m mutant hiv-1 reverse transcriptase (rt) ternary complex with a double stranded dna and an incoming datp (10.1128/AAC.00224-17 )
  • 5TXO: structure of q151m complex (a62v, v75i, f77l, f116y, q151m) mutant hiv-1 reverse transcriptase (rt) ternary complex with a double stranded dna and an incoming datp (10.1128/AAC.00224-17 )
  • 5TXP: structure of q151m complex (a62v, v75i, f77l, f116y, q151m) mutant hiv-1 reverse transcriptase (rt) ternary complex with a double stranded dna and an incoming ddatp (10.1128/AAC.00224-17 )
  • 5UV5: crystal structure of a 2-hydroxyisoquinoline-1,3-dione rnase h active site inhibitor with multiple binding modes to hiv reverse transcriptase (10.1128/AAC.01351-17 )
  • 5VQQ: crystal structure of hiv-1 reverse transcriptase in complex with n-(6- cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy) phenoxy)-4-methylnaphthalen-1-yl)-2-fluoro-n-methylacetamide (jlj683), a non-nucleoside inhibitor (10.1073/PNAS.1711463114 )
  • 5VQR: crystal structure of hiv-1 reverse transcriptase in complex with n-(6- cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy) phenoxy)-4-methylnaphthalen-1-yl)-n-methylacrylamide (jlj684), a non- nucleoside inhibitor (10.1073/PNAS.1711463114 )
  • 5VQS: crystal structure of hiv-1 reverse transcriptase in complex with n-(6- cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy) phenoxy)-4-methylnaphthalen-1-yl)acrylamide (jlj685), a non- nucleoside inhibitor (10.1073/PNAS.1711463114 )
  • 5VQT: crystal structure of hiv-1 reverse transcriptase in complex with 2- chloro-n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl) ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n-methylacetamide (jlj686), a non-nucleoside inhibitor (10.1073/PNAS.1711463114 )
  • 5VQU: crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin- 1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-2-fluoro-n- methylacetamide (jlj683), a non-nucleoside inhibitor (10.1073/PNAS.1711463114 )
  • 5VQV: crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin- 1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n-methylacrylamide (jlj684), a non-nucleoside inhibitor (10.1073/PNAS.1711463114 )
  • 5VQW: crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin- 1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)acrylamide (jlj685), a non-nucleoside inhibitor (10.1073/PNAS.1711463114 )
  • 5VQX: crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with 2-chloro-n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n- methylacetamide (jlj686), a non-nucleoside inhibitor (10.1073/PNAS.1711463114 )
  • 5VQY: crystal structure of hiv-1 reverse transcriptase (k103n, y181c) variant in complex with n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n- methylacrylamide (jlj684), a non-nucleoside inhibitor (10.1073/PNAS.1711463114 )
  • 5VQZ: crystal structure of hiv-1 reverse transcriptase (k103n, y181c) variant in complex with 2-chloro-n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n- methylacetamide (jlj686), a non-nucleoside inhibitor (10.1073/PNAS.1711463114 )
  • 5XN0: hiv-1 reverse transcriptase q151m:dna binary complex (10.1038/S41598-018-19602-9 )
  • 5XN1: hiv-1 reverse transcriptase q151m:dna:entecavir-triphosphate ternary complex (10.1038/S41598-018-19602-9 )
  • 5XN2: hiv-1 reverse transcriptase q151m:dna:dgtp ternary complex (10.1038/S41598-018-19602-9 )
  • 6AOC: crystal structure of an n-hydroxythienopyrimidine-2,4-dione rnase h active site inhibitor with multiple binding modes to hiv reverse transcriptase (10.1016/J.EJMECH.2017.09.054 )
  • 6C0J: crystal structure of hiv-1 reverse transcriptase in complex with non- nucleoside inhibitor k-5a2 (10.7554/ELIFE.36340 )
  • 6C0K: crystal structure of hiv-1 k103n mutant reverse transcriptase in complex with non-nucleoside inhibitor k-5a2 (10.7554/ELIFE.36340 )
  • 6C0L: crystal structure of hiv-1 e138k mutant reverse transcriptase in complex with non-nucleoside inhibitor k-5a2 (10.7554/ELIFE.36340 )
  • 6C0N: crystal structure of hiv-1 reverse transcriptase in complex with non- nucleoside inhibitor 25a (10.7554/ELIFE.36340 )
  • 6C0O: crystal structure of hiv-1 k103n mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a (10.7554/ELIFE.36340 )
  • 6C0P: crystal structure of hiv-1 e138k mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a (10.7554/ELIFE.36340 )
  • 6C0R: crystal structure of hiv-1 k103n/y181c mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a (10.7554/ELIFE.36340 )
  • 6CGF: crystal structure of hiv-1 y188l mutant reverse transcriptase in complex with non-nucleoside inhibitor k-5a2 (10.7554/ELIFE.36340 )
  • 6DTW: hiv-1 reverse transcriptase y181c mutant in complex with jlj 578 (10.1016/J.BMCL.2019.06.047 )
  • 6DTX: wildtype hiv-1 reverse transcriptase in complex with jlj 578 (10.1016/J.BMCL.2019.06.047 )
  • 6DUF: crystal structure of hiv-1 reverse transcriptase v106a/f227l mutant in complex with non-nucleoside inhibitor 25a (10.7554/ELIFE.36340 )
  • 6DUG: crystal structure of hiv-1 reverse transcriptase k101p mutant in complex with non-nucleoside inhibitor 25a (10.7554/ELIFE.36340 )
  • 6DUH: crystal structure of hiv-1 reverse transcriptase y181i mutant in complex with non-nucleoside inhibitor 25a (10.7554/ELIFE.36340 )
  • 6ECL: crystal structure of a 1,2,4-triazole allosteric rnase h inhibitor in complex with hiv reverse transcriptase
  • 6ELI: structure of hiv-1 reverse transcriptase (rt) in complex with rilpivirine and an rnase h inhibitor xz462 (10.1128/JVI.02203-17 )
  • 6IK9: hiv-1 reverse transcriptase with q151m/g112s/d113a/y115f/f116y/f160l/i159l:dna:dgtp ternary complex (10.1016/J.BBRC.2019.01.026 )
  • 6IKA: hiv-1 reverse transcriptase with q151m/g112s/d113a/y115f/f116y/f160l/i159l:dna:entecavir-triphosphate ternary complex (10.1016/J.BBRC.2019.01.026 )
  • 6KDJ: hiv-1 reverse transcriptase with q151m/y115f/f116y:dna:lamivudine 5'- triphosphate ternary complex (10.1038/S41598-020-59775-W )
  • 6KDK: hiv-1 reverse transcriptase with q151m/y115f/f116y:dna:dctp ternary complex (10.1038/S41598-020-59775-W )
  • 6KDM: hiv-1 reverse transcriptase with q151m/y115f/f116y:dna:entecavir 5'- triphosphate ternary complex (10.1038/S41598-020-59775-W )
  • 6KDN: hiv-1 reverse transcriptase with q151m/y115f/f116y:dna:dgtp ternary complex (10.1038/S41598-020-59775-W )
  • 6KDO: hiv-1 reverse transcriptase with q151m/y115f/f116y/m184v/f160m:dna:lamivudine 5'-triphosphate ternary complex (10.1038/S41598-020-59775-W )
  • 6O9E: structure of hiv-1 reverse transcriptase in complex with dna and indopy-1 (10.1021/ACS.JMEDCHEM.9B01289 )
  • 6OE3: crystal structure of hiv-1 reverse transcriptase in complex with 5-(2- (2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-7-fluoro- 2-naphthonitrile (jlj635), a non-nucleoside inhibitor (10.1016/J.ANTIVIRAL.2019.04.010 )
  • 6UL5: crystal structure of hiv-1 reverse transcriptase (rt) in complex with 4-[(4-{4-[(e)-2-cyanoethenyl]-2,6-dimethylphenoxy}thieno[3,2- d]pyrimidin-2-yl)amino]-2-fluorobenzonitrile (24b), a non-nucleoside rt inhibitor (10.1021/ACS.JMEDCHEM.9B01769 )
  • 6X47: crystal structure of hiv-1 reverse transcriptase in complex with 7-(2- (2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-2- naphthonitrile (jlj649), a non-nucleoside inhibitor (10.1002/PRO.3910 )
  • 6X49: crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with 7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl) ethoxy)phenoxy)-2-naphthonitrile (jlj649), a non-nucleoside inhibitor (10.1002/PRO.3910 )
  • 6X4A: crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with 5-chloro-7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)- yl)ethoxy)phenoxy)-8-methyl-2-naphthonitrile (jlj651), a non- nucleoside inhibitor (10.1002/PRO.3910 )
  • 6X4B: crystal structure of hiv-1 reverse transcriptase in complex with 7-(2- (2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-5-fluoro- 8-methyl-2-naphthonitrile (jlj655), a non-nucleoside inhibitor (10.1002/PRO.3910 )
  • 6X4C: crystal structure of hiv-1 reverse transcriptase in complex with 7-(2- (2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)-4-fluorophenoxy)- 5,8-dimethyl-2-naphthonitrile (jlj658), a non-nucleoside inhibitor (10.1002/PRO.3910 )
  • 6X4D: crystal structure of hiv-1 reverse transcriptase in complex with 5- (cyclopropylmethyl)-7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)- yl)ethoxy)phenoxy)-8-methyl-2-naphthonitrile (jlj678), a non- nucleoside inhibitor (10.1002/PRO.3910 )
  • 6X4E: crystal structure of hiv-1 reverse transcriptase in complex with methyl 2-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl) ethoxy)phenoxy)-4-methylnaphthalen-1-yl)acetate (jlj681), a non- nucleoside inhibitor (10.1002/PRO.3910 )
  • 6X4F: crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with methyl 2-(6-cyano-3-(2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl) acetate (jlj681), a non-nucleoside inhibitor (10.1002/PRO.3910 )
  • 7AHX: hiv-1 reverse transcriptase complex with dna and d-aspartate tenofovir with bound manganese (10.1021/ACS.JMEDCHEM.0C01747 )
  • 7AID: hiv-1 reverse transcriptase complex with dna and d-aspartate tenofovir (10.1021/ACS.JMEDCHEM.0C01747 )
  • 7AIF: hiv-1 reverse transcriptase complex with dna and l-glutamate tenofovir with bound manganese (10.1021/ACS.JMEDCHEM.0C01747 )
  • 7AIG: hiv-1 reverse transcriptase complex with dna and l-glutamate tenofovir (10.1021/ACS.JMEDCHEM.0C01747 )
  • 7AII: hiv-1 reverse transcriptase complex with dna and l-methionine tenofovir with bound manganese (10.1021/ACS.JMEDCHEM.0C01747 )
  • 7AIJ: hiv-1 reverse transcriptase complex with dna and l-methionine tenofovir (10.1021/ACS.JMEDCHEM.0C01747 )
  • 7KRC: crystal structure of hiv-1 reverse transcriptase in complex with (e)- 4-(3-chloro-5-(2-cyanovinyl)phenoxy)-3-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenyl sulfurofluoridate (jlj709) (10.1021/ACSMEDCHEMLETT.0C00612 )
  • 7KRD: crystal structure of hiv-1 reverse transcriptase in complex with 4-(3- chloro-5-cyanophenoxy)-3-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)- yl)ethoxy)phenyl sulfurofluoridate (jlj702) (10.1021/ACSMEDCHEMLETT.0C00612 )
  • 7KRE: crystal structure of hiv-1 reverse transcriptase in complex with 4- ((6-cyanonaphthalen-1-yl)oxy)-3-(2-(2,4-dioxo-3,4-dihydropyrimidin- 1(2h)-yl)ethoxy)phenyl sulfurofluoridate (jlj704) (10.1021/ACSMEDCHEMLETT.0C00612 )
  • 7KRF: crystal structure of hiv-1 reverse transcriptase in complex with (e)- 4-(3-(2-cyanovinyl)-5-fluorophenoxy)-3-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenyl sulfurofluoridate (jlj710) (10.1021/ACSMEDCHEMLETT.0C00612 )
  • 7KWU: crystal structure of hiv-1 rt in complex with 16c (k07-15) (10.1021/ACS.JMEDCHEM.1C00268 )