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Found 74 with Last Name = 'abdul-hay' and Initial = 'so'
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427698(CHEMBL2324206)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human recombinant IDE-mediated fluorescein-Abeta-(1-40)-Lys-biotin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427703(CHEMBL2324220)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427703(CHEMBL2324220)
Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant IDE-mediated fluorescein-Abeta-(1-40)-Lys-biotin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427697(CHEMBL2324207)
Affinity DataKi:  23nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427696(CHEMBL2324201)
Affinity DataKi:  26nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427703(CHEMBL2324220)
Affinity DataKi:  38nMAssay Description:Inhibition of human recombinant IDE-mediated insulin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427698(CHEMBL2324206)
Affinity DataKi:  44nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427700(CHEMBL2324204)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427696(CHEMBL2324201)
Affinity DataKi:  70nMAssay Description:Inhibition of human recombinant IDE-mediated fluorescein-Abeta-(1-40)-Lys-biotin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427713(CHEMBL2324209)
Affinity DataKi:  73nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427715(CHEMBL2324219)
Affinity DataKi:  78nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427699(CHEMBL2324205)
Affinity DataKi:  85nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427701(CHEMBL2324203)
Affinity DataKi:  87nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427702(CHEMBL2324202)
Affinity DataKi:  103nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427701(CHEMBL2324203)
Affinity DataKi:  107nMAssay Description:Inhibition of human recombinant IDE-mediated fluorescein-Abeta-(1-40)-Lys-biotin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427697(CHEMBL2324207)
Affinity DataKi:  171nMAssay Description:Inhibition of human recombinant IDE-mediated insulin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427700(CHEMBL2324204)
Affinity DataKi:  228nMAssay Description:Inhibition of human recombinant IDE-mediated fluorescein-Abeta-(1-40)-Lys-biotin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427697(CHEMBL2324207)
Affinity DataKi:  246nMAssay Description:Inhibition of human recombinant IDE-mediated fluorescein-Abeta-(1-40)-Lys-biotin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427696(CHEMBL2324201)
Affinity DataKi:  275nMAssay Description:Inhibition of human recombinant IDE-mediated insulin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427699(CHEMBL2324205)
Affinity DataKi:  365nMAssay Description:Inhibition of human recombinant IDE-mediated fluorescein-Abeta-(1-40)-Lys-biotin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427698(CHEMBL2324206)
Affinity DataKi:  410nMAssay Description:Inhibition of human recombinant IDE-mediated insulin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427709(CHEMBL2324213)
Affinity DataKi:  498nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427699(CHEMBL2324205)
Affinity DataKi:  833nMAssay Description:Inhibition of human recombinant IDE-mediated insulin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427702(CHEMBL2324202)
Affinity DataKi:  927nMAssay Description:Inhibition of human recombinant IDE-mediated fluorescein-Abeta-(1-40)-Lys-biotin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427714(CHEMBL2324208)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427701(CHEMBL2324203)
Affinity DataKi:  1.28E+3nMAssay Description:Inhibition of human recombinant IDE-mediated insulin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427702(CHEMBL2324202)
Affinity DataKi:  1.89E+3nMAssay Description:Inhibition of human recombinant IDE-mediated insulin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427700(CHEMBL2324204)
Affinity DataKi:  3.26E+3nMAssay Description:Inhibition of human recombinant IDE-mediated insulin degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427704(CHEMBL2324218)
Affinity DataKi:  5.28E+3nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427708(CHEMBL2324214)
Affinity DataKi:  7.02E+3nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427710(CHEMBL2324212)
Affinity DataKi:  7.75E+3nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427711(CHEMBL2324211)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427712(CHEMBL2324210)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427707(CHEMBL2324215)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427705(CHEMBL2324217)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427706(CHEMBL2324216)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)
Affinity DataIC50:  15nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)
Affinity DataIC50:  29nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254744(CHEMBL474057 | N8-((2S,3R)-4-(cyclopropylamino)-3-...)
Affinity DataIC50:  56nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254714(CHEMBL473854 | N7-((2S,3R)-4-(cyclopropylamino)-3-...)
Affinity DataIC50:  63nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254785(CHEMBL464918 | N6-((2S,3R)-4-(cyclopropylamino)-3-...)
Affinity DataIC50:  89nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254784(CHEMBL517179 | N5-((2S,3R)-4-(cyclopropylamino)-3-...)
Affinity DataIC50:  112nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)
Affinity DataIC50:  132nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254711(CHEMBL443087 | N-((1S,2R)-1-Benzyl-3-cyclopropylam...)
Affinity DataIC50:  141nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254712(CHEMBL499468 | N-((1S,2R)-1-Benzyl-3-cyclopropylam...)
Affinity DataIC50:  158nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254712(CHEMBL499468 | N-((1S,2R)-1-Benzyl-3-cyclopropylam...)
Affinity DataIC50:  251nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254746(CHEMBL446879 | N8-((2S,3R)-4-(cyclopropylamino)-3-...)
Affinity DataIC50:  262nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254713(CHEMBL514310 | N6-((2S,3R)-4-(cyclopropylamino)-3-...)
Affinity DataIC50:  524nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254745(CHEMBL463864 | N7-((2S,3R)-4-(cyclopropylamino)-3-...)
Affinity DataIC50:  740nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254708(4'-Chloro-biphenyl-3,5-dicarboxylic acid 3-[((1S,2...)
Affinity DataIC50:  811nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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