Compile Data Set for Download or QSAR
maximum 50k data
Found 241 with Last Name = 'abel' and Initial = 'b'
TargetKappa-type opioid receptor(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603613(CHEMBL5169644)
Affinity DataKi:  210nMAssay Description:Binding affinity towards human kappa opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603613(CHEMBL5169644)
Affinity DataKi:  483nMAssay Description:Binding affinity towards human adenosine A3 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603612(CHEMBL5171777)
Affinity DataKi:  6.82E+3nMAssay Description:Binding affinity towards human adenosine A3 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A3(Mus musculus)
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603613(CHEMBL5169644)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards mouse adenosine A3 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)
Affinity DataIC50:  40nMAssay Description:Inhibition of CYP3A4 (unknown origin) expressed in baculosomesMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50247405(CHEMBL4077753)
Affinity DataIC50:  100nMAssay Description:Displacement of [125I]-IAAP from human P-gp expressed in high five insect cell membrane vesicles preincubated for 10 mins followed by photocrosslinki...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435227(CHEMBL2392772)
Affinity DataIC50:  360nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603613(CHEMBL5169644)
Affinity DataIC50:  440nMAssay Description:Inhibition of human ABCG2 in human R5 cells assessed as inhibition of mitoxantrone efflux measured by flow cytometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435224(CHEMBL2392893)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603614(CHEMBL5196742)
Affinity DataIC50:  600nMAssay Description:Inhibition of human ABCG2 in human R5 cells assessed as inhibition of mitoxantrone efflux measured by flow cytometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435217(CHEMBL2392900)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50247406(CHEMBL4089061)
Affinity DataIC50:  760nMAssay Description:Displacement of [125I]-IAAP from human P-gp expressed in high five insect cell membrane vesicles preincubated for 10 mins followed by photocrosslinki...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435218(CHEMBL2392899)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435226(CHEMBL2392891)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435219(CHEMBL2392898)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50433375(CHEMBL472879 | GNF-Pf-359)
Affinity DataIC50:  860nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435229(CHEMBL2392771)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435228(CHEMBL460432)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435225(CHEMBL2392892)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435223(CHEMBL2392894)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435220(CHEMBL2392897)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435222(CHEMBL2392895)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435231(CHEMBL2392769)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435221(CHEMBL2392896)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50433377(CHEMBL2375628)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603616(CHEMBL5185009)
Affinity DataIC50:  2.57E+3nMAssay Description:Inhibition of human ABCG2-mediated ATPase activity preincubated for 2 mins followed by ATP addition and measured after 20 mins by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603615(CHEMBL5177814)
Affinity DataIC50:  2.59E+3nMAssay Description:Inhibition of human ABCG2-mediated ATPase activity preincubated for 2 mins followed by ATP addition and measured after 20 mins by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603617(CHEMBL5208602)
Affinity DataIC50:  4.01E+3nMAssay Description:Inhibition of human ABCG2-mediated ATPase activity preincubated for 2 mins followed by ATP addition and measured after 20 mins by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435237(CHEMBL2392764)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603612(CHEMBL5171777)
Affinity DataIC50:  4.98E+3nMAssay Description:Inhibition of human ABCG2 in human R5 cells assessed as inhibition of mitoxantrone efflux measured by flow cytometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50247407(CHEMBL4076355)
Affinity DataIC50:  8.23E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435230(CHEMBL2392770)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50433375(CHEMBL472879 | GNF-Pf-359)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435218(CHEMBL2392899)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435234(CHEMBL2392766)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435232(CHEMBL2392768)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435231(CHEMBL2392769)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435230(CHEMBL2392770)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM74255((3-amino-2-methyl-phenyl)amine | 1,3-Benzenediamin...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of full length PI3Kalpha (unknown origin) assessed as reduction in PIP3 formation using PIP2 as substrate after 45 mins by fluorescence po...More data for this Ligand-Target Pair
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435224(CHEMBL2392893)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM26188(α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of full length PI3Kalpha (unknown origin) assessed as reduction in PIP3 formation using PIP2 as substrate after 45 mins by fluorescence po...More data for this Ligand-Target Pair
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435237(CHEMBL2392764)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435217(CHEMBL2392900)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435236(CHEMBL2392765)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435235(CHEMBL454036)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435233(CHEMBL2392767)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435236(CHEMBL2392765)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435235(CHEMBL454036)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435234(CHEMBL2392766)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435233(CHEMBL2392767)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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