Affinity DataIC50: 0.251nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Inhibition of N-terminal His-Smt-tagged MSK1 C-terminal kinase domain (414 to 738 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of PMX in Plasmodium falciparum 3D7 HA epitopeMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of MSK2 (unknown origin) FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by activation with ERK2 and substrate addi...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University
Curated by ChEMBL
Northern Illinois University
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of MSK2 (unknown origin) FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by activation with ERK2 and substrate addi...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 119nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Inhibition of Plasmodium falciparum PMIX by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Inhibition of PMIX in Plasmodium falciparum 3D7 HA epitopeMore data for this Ligand-Target Pair