Found 119 with Last Name = 'adams' and Initial = 'dj' 
Affinity DataKi: 20nM ΔG°: -45.7kJ/molepH: 5.5 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
Affinity DataKi: 124nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
Affinity DataKi: 7.90E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+4nM ΔG°: -26.6kJ/molepH: 5.5 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Beijing Institute Of Biotechnology
Curated by ChEMBL
Beijing Institute Of Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-curr...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Beijing Institute Of Biotechnology
Curated by ChEMBL
Beijing Institute Of Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-curr...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage cl...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Beijing Institute Of Biotechnology
Curated by ChEMBL
Beijing Institute Of Biotechnology
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-curr...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
TargetNicotinic acetylcholine receptor alpha9/alpha10(RAT)
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of rat alpha9alpha10 nAChRMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Beijing Institute Of Biotechnology
Curated by ChEMBL
Beijing Institute Of Biotechnology
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-curr...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 5.84nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNicotinic acetylcholine receptor alpha9/alpha10(RAT)
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Inhibition of rat alpha9alpha10 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 9.60nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 5.2 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
3D Structure (crystal)TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Beijing Institute Of Biotechnology
Curated by ChEMBL
Beijing Institute Of Biotechnology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Agonist activity at human GABAB expressed in HEK293T cells co-transfected with human CaV2.2 channel assessed as inhibition of CaV2.2-mediated Ba2+ pe...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Beijing Institute Of Biotechnology
Curated by ChEMBL
Beijing Institute Of Biotechnology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-curr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Beijing Institute Of Biotechnology
Curated by ChEMBL
Beijing Institute Of Biotechnology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-curr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Beijing Institute Of Biotechnology
Curated by ChEMBL
Beijing Institute Of Biotechnology
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Agonist activity at human GABAB expressed in HEK293T cells co-transfected with human CaV2.2 channel assessed as inhibition of CaV2.2-mediated Ba2+ pe...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage cl...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Beijing Institute Of Biotechnology
Curated by ChEMBL
Beijing Institute Of Biotechnology
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-curr...More data for this Ligand-Target Pair
TargetNicotinic acetylcholine receptor alpha9/alpha10(RAT)
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -80 mV holding potential ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage cl...More data for this Ligand-Target Pair
TargetNicotinic acetylcholine receptor alpha9/alpha10(RAT)
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of rat alpha9/alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced currents after 300 secs by two-el...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Queensland
Curated by ChEMBL
University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Activity at rat alpha7 nAChR expressed in Xenopus laevis assessed as inhibition of acetylcholine-induced current at holding potential of -80 mV by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage clamp ass...More data for this Ligand-Target Pair
TargetNicotinic acetylcholine receptor alpha9/alpha10(RAT)
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of rat alpha9/alpha10 nAChR expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced currents after 300 secs by two-el...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Queensland
Curated by ChEMBL
University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Queensland
Curated by ChEMBL
University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Activity at rat alpha7 nAChR expressed in Xenopus laevis assessed as inhibition of acetylcholine-induced current at holding potential of -80 mV by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNicotinic acetylcholine receptor alpha9/alpha10(RAT)
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of rat alpha9alpha10 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Queensland
Curated by ChEMBL
University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Activity at rat alpha7 nAChR expressed in Xenopus laevis assessed as inhibition of acetylcholine-induced current at holding potential of -80 mV by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Ocean University Of China
Curated by ChEMBL
Ocean University Of China
Curated by ChEMBL
Affinity DataIC50: 117nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes expressing alpha9:alpha10 mRNA injection ratio of 1:3 assessed as inhibit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Queensland
Curated by ChEMBL
University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 207nMAssay Description:Activity at rat alpha7 nAChR expressed in Xenopus laevis assessed as inhibition of acetylcholine-induced current at holding potential of -80 mV by tw...More data for this Ligand-Target Pair
