Affinity DataIC50: 5nMAssay Description:Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Griffith University
Curated by ChEMBL
Griffith University
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Griffith University
Curated by ChEMBL
Griffith University
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]SAM from Icmt relative to SAHMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Griffith University
Curated by ChEMBL
Griffith University
Curated by ChEMBL
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Griffith University
Curated by ChEMBL
Griffith University
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Icmt using [3H]SAM as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...More data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at human adrenergic alpha2B receptor expressed in HEK293 cells coexpressing Gqi5 protein by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.20E+3nMAssay Description:Agonist activity at human adrenergic alpha2B receptor expressed in HEK293 cells coexpressing Gqi5 protein by FLIPR assayMore data for this Ligand-Target Pair