Compile Data Set for Download or QSAR
maximum 50k data
Found 9 with Last Name = 'addepalli' and Initial = 'r'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataIC50:  5nMAssay Description:Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50225276(6-(3,3'-dihydroxy-4'-sulfooxy-biphenyl-4-yloxy)-2,...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50225828((2Z,2'Z)-N,N'-{butane-1,4-diylbis[(methylimino)pro...)
Affinity DataIC50:  1.90E+3nMAssay Description:Displacement of [3H]SAM from Icmt relative to SAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50225277(2,8-dihydroxy-6-(3,3',4'-trihydroxy-biphenyl-4-ylo...)
Affinity DataIC50:  3.71E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50479260(APLYSAMINE 6)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Icmt using [3H]SAM as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50174412(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50090256((R)-2-((S)-1,2-dihydroxyethyl)-4,5-dihydroxyfuran-...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human adrenergic alpha2B receptor expressed in HEK293 cells coexpressing Gqi5 protein by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50250521((-)-dibromophakellin | CHEMBL447696 | dibromophake...)
Affinity DataEC50:  4.20E+3nMAssay Description:Agonist activity at human adrenergic alpha2B receptor expressed in HEK293 cells coexpressing Gqi5 protein by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed