Affinity DataKi: 2.5nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 99nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against Hras Farnesyltransferase (FPT).More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against Hras Farnesyltransferase (FPT).More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of [3H]-FPP incorporation into His6-H-Ras-CVLS by farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibitory activity against Hras Farnesyltransferase (FPT).More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 1.90nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity against Hras Farnesyltransferase (FPT).More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity against Hras Farnesyltransferase (FPT).More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Hras Farnesyltransferase (FPT).More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Hras Farnesyltransferase (FPT).More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibitory activity against Hras Farnesyltransferase (FPT).More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Hras Farnesyl protein transferase(FPT)More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of [3H]-FPP incorporation into His6-H-Ras-CVLS by farnesyl transferaseMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity against Hras Farnesyltransferase (FPT).More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Hras Farnesyl protein transferase(FPT)More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Hras Farnesyl protein transferase(FPT)More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibitory activity against Hras Farnesyltransferase (FPT).More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair