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Found 26 with Last Name = 'aggarwal' and Initial = 's'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293605(1-(4-aminophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50182555(1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293604(1-(4-amino-3-iodophenyl)-2-pyrrolidin-1-yl-pentan-...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293606(1-(4-azio-3-iodophenyl)-2-pyrroldin-1-yl-pentan-1-...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50048392(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Affinity DataKi:  441nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50363131(CHEMBL1946574)
Affinity DataKi:  3.07E+3nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in N2A cells after 15 mins by photoaffinity labelingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293605(1-(4-aminophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50141090(CHEMBL3753791)
Affinity DataIC50:  16nMAssay Description:Inhibition of human 5alpha-2 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione incubated for 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50396331(CHEMBL2172644)
Affinity DataIC50:  22.1nMAssay Description:Inhibition of human type-2 5-alpha reductase expressed in HEK293 cells using [3H]-androstenedione as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50396329(CHEMBL2172647)
Affinity DataIC50:  26.5nMAssay Description:Inhibition of human type-2 5-alpha reductase expressed in HEK293 cells using [3H]-androstenedione as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  30.3nMAssay Description:Inhibition of human type-2 5-alpha reductase expressed in HEK293 cells using [3H]-androstenedione as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50182555(1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)
Affinity DataIC50:  32nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human 5alpha-2 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione incubated for 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50396332(CHEMBL2172643)
Affinity DataIC50:  54.1nMAssay Description:Inhibition of human type-2 5-alpha reductase expressed in HEK293 cells using [3H]-androstenedione as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50396330(CHEMBL2172645)
Affinity DataIC50:  72.8nMAssay Description:Inhibition of human type-2 5-alpha reductase expressed in HEK293 cells using [3H]-androstenedione as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50141068(CHEMBL3754525)
Affinity DataIC50:  84nMAssay Description:Inhibition of human 5alpha-2 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione incubated for 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50141093(CHEMBL3754321)
Affinity DataIC50:  157nMAssay Description:Inhibition of human 5alpha-2 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione incubated for 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293604(1-(4-amino-3-iodophenyl)-2-pyrrolidin-1-yl-pentan-...)
Affinity DataIC50:  175nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50396328(CHEMBL2172650)
Affinity DataIC50:  213nMAssay Description:Inhibition of human type-2 5-alpha reductase expressed in HEK293 cells using [3H]-androstenedione as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50141091(CHEMBL3752475)
Affinity DataIC50:  220nMAssay Description:Inhibition of human 5alpha-2 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione incubated for 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293606(1-(4-azio-3-iodophenyl)-2-pyrroldin-1-yl-pentan-1-...)
Affinity DataIC50:  264nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50141092(CHEMBL3753825)
Affinity DataIC50:  274nMAssay Description:Inhibition of human 5alpha-2 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione incubated for 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  453nMAssay Description:Inhibition of human 5alpha-1 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione incubated for 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  453nMAssay Description:Inhibition of human type-1 5-alpha reductase expressed in HEK293 cells using [3H]-androstenedione as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50141090(CHEMBL3753791)
Affinity DataIC50:  547nMAssay Description:Inhibition of human 5alpha-1 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione incubated for 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50048392(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank