TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University Of Cambridge
Curated by ChEMBL
University Of Cambridge
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Competitive inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 1.93nMAssay Description:Displacement of [3H]WIN35,428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 3.26nMAssay Description:Displacement of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 22.5nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 31.0nMAssay Description:Displacement of [3H]NE from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University Of Cambridge
Curated by ChEMBL
University Of Cambridge
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate assessed as...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]5-HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKd: 9nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKd: 4nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair