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Found 15 with Last Name = 'akabas' and Initial = 'mh'
TargetGamma-aminobutyric acid receptor subunit alpha-6(RAT)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273002(5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [3H]Muscimol from GABAAalpha6 receptor in Sprague-Dawley rat brain cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6(RAT)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273003(CHEMBL456781 | [5-(2-Amino-ethyl)-3H-[1,3,4]oxadia...)
Affinity DataIC50:  7.40E+3nMAssay Description:Displacement of [3H]Muscimol from GABAAalpha6 receptor in Sprague-Dawley rat brain cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6(RAT)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273043(5-Aminomethyl-3H-[1,3,4]oxadiazol-2-thione Hydroch...)
Affinity DataIC50:  4.90E+4nMAssay Description:Displacement of [3H]Muscimol from GABAAalpha6 receptor in Sprague-Dawley rat brain cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273004(5-Piperidin-4-yl-3H-[1,3,4]oxadiazol-2-thione Hydr...)
Affinity DataIC50:  5.90E+4nMAssay Description:Agonist activity at rat wild type GABAAalpha1beta2 receptor expressed in Xenopus laevis oocytes as inhibition of GABA-induced current at -60 mV by Tw...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6(RAT)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273004(5-Piperidin-4-yl-3H-[1,3,4]oxadiazol-2-thione Hydr...)
Affinity DataIC50:  6.60E+4nMAssay Description:Displacement of [3H]Muscimol from GABAAalpha6 receptor in Sprague-Dawley rat brain cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6(RAT)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273110(4-(5-Methyl-[1,3,4]oxadiazol-2-yl)-piperidine Hydr...)
Affinity DataIC50:  7.60E+4nMAssay Description:Displacement of [3H]Muscimol from GABAAalpha6 receptor in Sprague-Dawley rat brain cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6(RAT)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273001(5-Piperidin-4-yl-3H-[1,3,4]oxadiazol-2-one Hydroch...)
Affinity DataIC50:  1.23E+5nMAssay Description:Displacement of [3H]Muscimol from GABAAalpha6 receptor in Sprague-Dawley rat brain cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(RAT)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273002(5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...)
Affinity DataEC50:  1.37E+5nMAssay Description:Agonist activity at rat recombinant GABAAalpha5beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6(RAT)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273002(5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...)
Affinity DataEC50:  3.00E+4nMAssay Description:Agonist activity at rat recombinant GABAAalpha6beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273002(5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...)
Affinity DataEC50:  2.80E+5nMAssay Description:Agonist activity at rat recombinant GABAAalpha1beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(RAT)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273002(5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...)
Affinity DataEC50:  2.30E+6nMAssay Description:Agonist activity at rat recombinant GABAAalpha3beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Affinity DataEC50:  1.00E+4nMAssay Description:Activity at rat wild type GABAAalpha1beta2 receptor expressed in Xenopus laevis oocytes at -60 mV by Two-Electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273002(5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...)
Affinity DataEC50:  1.82E+5nMAssay Description:Agonist activity at rat recombinant GABAAalpha2beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273004(5-Piperidin-4-yl-3H-[1,3,4]oxadiazol-2-thione Hydr...)
Affinity DataEC50:  9.50E+6nMAssay Description:Agonist activity at rat wild type GABAAalpha1beta2 receptor expressed in Xenopus laevis oocytes at -60 mV by Two-Electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rattus norvegicus (Rat))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50273002(5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...)
Affinity DataEC50:  1.28E+5nMAssay Description:Agonist activity at rat recombinant GABAAalpha4beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed