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Found 34 with Last Name = 'akber ansari' and Initial = 's'
TargetAcetylcholinesterase(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513900(CHEMBL4444582)
Affinity DataKi:  61nMAssay Description:Inhibition of Acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513907(CHEMBL4579543)
Affinity DataKi:  61nMAssay Description:Inhibition of Acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513912(CHEMBL4524569)
Affinity DataKi:  61nMAssay Description:Inhibition of Acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513908(CHEMBL4453373)
Affinity DataKi:  61nMAssay Description:Inhibition of Acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513909(CHEMBL4541764)
Affinity DataKi:  61nMAssay Description:Inhibition of Acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513904(CHEMBL4546114)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human PARP1 expressed in Escherichia coli incubated for 15 to 40 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513902(CHEMBL4442022)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human PARP1 expressed in Escherichia coli incubated for 15 to 40 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513901(CHEMBL4579526)
Affinity DataIC50:  2nMAssay Description:Inhibition of human PARP1 expressed in Escherichia coli using histone as substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human placenta Aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50006469(CHEMBL69956 | [8-Oxo-7-(5-trifluoromethyl-benzothi...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human Aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50268124(CHEMBL4078014)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009781(CHEMBL20169 | [3-(5-Bromo-benzothiazol-2-ylmethyl)...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human placenta Aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50008471(CHEMBL143234 | [3-(5,7-Difluoro-benzooxazol-2-ylme...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human placenta Aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50006481(CHEMBL73560 | [1-(5,7-Difluoro-benzothiazol-2-ylme...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human Aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of PARP1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50006471(CHEMBL68580 | [4-Oxo-3-(5-trifluoromethyl-benzothi...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human Aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50268134(CHEMBL4097093)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of PARP1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of human PARP1 expressed in Escherichia coli incubated for 10 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513903(CHEMBL4547590)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of human PARP1 expressed in Escherichia coli incubated for 10 mins by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50006463((3-Benzothiazol-2-ylmethyl-4-oxo-3,4-dihydro-phtha...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human placenta Aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513914(CHEMBL4436968)
Affinity DataIC50:  20nMAssay Description:Inhibition of human Aldose reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513913(CHEMBL4458061)
Affinity DataIC50:  46nMAssay Description:Inhibition of human Aldose reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50028859(CHEMBL3342698)
Affinity DataIC50: <50nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-beta induced PGE2 release preincubated for 30 mins followed by IL-beta addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513910(CHEMBL4450818)
Affinity DataIC50:  97nMAssay Description:Inhibition of N-terminal GST-tagged human PARP1 expressed in a Baculovirus infected Sf9 insect cells using biotinylated substrate incubated for 1 hr ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50: <100nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50: <100nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  139nMAssay Description:Inhibition of N-terminal GST-tagged human PARP1 expressed in a Baculovirus infected Sf9 insect cells using biotinylated substrate incubated for 1 hr ...More data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513905(CHEMBL4475847)
Affinity DataIC50:  420nMAssay Description:Inhibition of C-terminal His4-tagged Aurora A (unknown origin) using PKB-GSK2 biotinylated peptide as substrate incubated for 90 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  426nMAssay Description:Inhibition of Acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513911(CHEMBL4580842)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human PARP1 expressed in Escherichia coli incubated for 15 to 40 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50513906(CHEMBL4549769)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of ovine COX1 preincubated for 5 mins followed by arachidonic acid addition and measured after 2 mins by colorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of ovine COX1 preincubated for 5 mins followed by arachidonic acid addition and measured after 2 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM160509(US10280160, Example 1. | US9682969, 1)
Affinity DataEC50: <1.00E+4nMAssay Description:Inhibition of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing YFP-H148Q/I152L 25,22 incubated for 60 to 120 mins in presence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed