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Found 509 with Last Name = 'akunne' and Initial = 'hc'
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290221(CHEMBL80919 | Thiophene-2-carboxylic acid (4-{2-[4...)
Affinity DataKi:  0.0200nMAssay Description:Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50123626((S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of [3H]- prazosin binding against Alpha-1A adrenergic receptor from rat submaxillary glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343274(7-(4-(4-(5,6,7,8-tetrahydronaphthalen-1-yl)piperaz...)
Affinity DataKi:  0.0900nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343260(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  0.130nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063279(CHEMBL309623 | Cyclohexanecarboxylic acid {4-[2-(4...)
Affinity DataKi:  0.140nMAssay Description:Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343277(7-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)-3,...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010621(6-[Propyl-(2-thiophen-3-yl-ethyl)-amino]-5,6,7,8-t...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of [3H]- prazosin binding against Alpha-1B adrenergic receptor from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343273(7-(4-(4-(2,3-dihydro-1H-inden-4-yl)piperazin-1-yl)...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343276(7-(4-(4-(chroman-8-yl)piperazin-1-yl)butoxy)-3,4-d...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343283(7-(4-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.280nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343268(7-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  0.350nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50052535(3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50002173(3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity against human Dopamine receptor D3 in CHO-K1 cells using [3H]-Spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343266(7-(4-(4-(2-chloro-3-methylphenyl)piperazin-1-yl)bu...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50054070(6-Propylamino-5,6,7,8-tetrahydro-naphthalen-1-ol |...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  0.5nMAssay Description:Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290206(CHEMBL78800 | Thiophene-2-carboxylic acid (4-{2-[4...)
Affinity DataKi:  0.5nMAssay Description:Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50115277((2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphtha...)
Affinity DataKi:  0.540nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  0.570nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290225(CHEMBL78950 | Thiophene-2-carboxylic acid (4-{2-[4...)
Affinity DataKi:  0.600nMAssay Description:Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  0.600nMAssay Description:Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50290221(CHEMBL80919 | Thiophene-2-carboxylic acid (4-{2-[4...)
Affinity DataKi:  0.600nMAssay Description:Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054077(7-Propylamino-5,6,7,8-tetrahydro-naphthalen-2-ol |...)
Affinity DataKi:  0.660nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50054075(7-(Methyl-propyl-amino)-5,6,7,8-tetrahydro-naphtha...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343284(7-(4-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50052531(4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-...)
Affinity DataKi:  0.670nMAssay Description:Binding affinityagainst Dopamine receptor D2 in CHO-K1 cells using radioligand [3H]-NPA binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50343276(7-(4-(4-(chroman-8-yl)piperazin-1-yl)butoxy)-3,4-d...)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054069(7-(Ethyl-methyl-amino)-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  0.710nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054075(7-(Methyl-propyl-amino)-5,6,7,8-tetrahydro-naphtha...)
Affinity DataKi:  0.740nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054070(6-Propylamino-5,6,7,8-tetrahydro-naphthalen-1-ol |...)
Affinity DataKi:  0.75nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054082(7-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-t...)
Affinity DataKi:  0.75nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50054082(7-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-t...)
Affinity DataKi:  0.760nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343284(7-(4-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343275(7-(4-(4-(chroman-5-yl)piperazin-1-yl)butoxy)-3,4-d...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343259(7-(5-(4-(2,3-dichlorophenyl)piperazin-1-yl)pentyl)...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50063291(CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...)
Affinity DataKi:  0.800nMAssay Description:Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50343277(7-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)-3,...)
Affinity DataKi:  0.810nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343278(7-(4-(4-(2-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  0.910nMAssay Description:Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343271(7-(4-(4-(2-chloro-3-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50343263(2-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50343282(7-(4-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)bu...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50343275(7-(4-(4-(chroman-5-yl)piperazin-1-yl)butoxy)-3,4-d...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50343273(7-(4-(4-(2,3-dihydro-1H-inden-4-yl)piperazin-1-yl)...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50343271(7-(4-(4-(2-chloro-3-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50343270(7-(4-(4-(3-chloro-2-fluorophenyl)piperazin-1-yl)bu...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50343260(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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