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Found 84 with Last Name = 'al-abed' and Initial = 'y'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50209085(3-fluoro-4-hydroxybenzaldehyde (4-methoxyphenyl)hy...)
Affinity DataIC50:  130nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50209081(3-chloro-4-hydroxybenzaldehyde (4-methoxyphenyl)hy...)
Affinity DataIC50:  220nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50209089(3-bromo-4-hydroxybenzaldehyde (4-methoxyphenyl)hyd...)
Affinity DataIC50:  330nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50209090(4-hydroxybenzaldehyde (4-methoxyphenyl)hydrazone |...)
Affinity DataIC50:  480nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186440((R)-1-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroiso...)
Affinity DataIC50:  550nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186444(CHEMBL211882 | neopentyl 2-(3-(3-fluoro-4-hydroxyp...)
Affinity DataIC50:  750nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186438((S)-1-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroiso...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50373155(CHEMBL253951)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of MIF-mediated dopachrome tautomerase activityMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186443(CHEMBL210592 | US8618147, 16 | neopentyl 2-(3-(4-h...)
Affinity DataIC50:  1.50E+3nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186443(CHEMBL210592 | US8618147, 16 | neopentyl 2-(3-(4-h...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50113768((S)-methyl 2-(4-hydroxybenzylideneamino)-3-(1H-ind...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50113768((S)-methyl 2-(4-hydroxybenzylideneamino)-3-(1H-ind...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186445(CHEMBL209401 | US8618147, 14 | cyclohexyl 2-(3-(4-...)
Affinity DataIC50:  2.50E+3nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186445(CHEMBL209401 | US8618147, 14 | cyclohexyl 2-(3-(4-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50209091(4-hydroxybenzaldehyde phenylhydrazone | CHEMBL2240...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50373156(CHEMBL253950)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of MIF-mediated dopachrome tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186429(CHEMBL210755 | US8618147, 13 | butyl 2-(3-(4-hydro...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186429(CHEMBL210755 | US8618147, 13 | butyl 2-(3-(4-hydro...)
Affinity DataIC50:  3.00E+3nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50373163(CHEMBL256939)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of MIF-mediated dopachrome tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186439(CHEMBL208659 | US8618147, 11 | propyl 2-(3-(4-hydr...)
Affinity DataIC50:  4.00E+3nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186439(CHEMBL208659 | US8618147, 11 | propyl 2-(3-(4-hydr...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50373157(CHEMBL257350)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of MIF-mediated dopachrome tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186430(CHEMBL377184 | US8618147, 15 | cyclohexylmethyl 2-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186430(CHEMBL377184 | US8618147, 15 | cyclohexylmethyl 2-...)
Affinity DataIC50:  5.00E+3nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50209092(CHEMBL221727 | tert-butyl-2-(4-hydroxybenzylidene)...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186425(CHEMBL208716 | US8618147, 12 | isopropyl 2-(3-(4-h...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186425(CHEMBL208716 | US8618147, 12 | isopropyl 2-(3-(4-h...)
Affinity DataIC50:  6.00E+3nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186427(CHEMBL212313 | methyl 2-(3-(3-fluoro-4-hydroxyphen...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50209080(CHEMBL384671 | methyl 2-(3-(4-hydroxyphenyl)-4,5-d...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186434((R)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50373164(CHEMBL256314)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of MIF-mediated dopachrome tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50373159(CHEMBL256315)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of MIF-mediated dopachrome tautomerase activityMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50373154(CHEMBL257614)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of MIF-mediated dopachrome tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50209083(4-methoxybenzyl-2-(4-hydroxybenzylidene)hydrazinec...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM111576(US8618147, 3)
Affinity DataIC50:  8.50E+3nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186431(CHEMBL210529 | US8618147, 8 | tert-butyl 4-(2-(3-(...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186431(CHEMBL210529 | US8618147, 8 | tert-butyl 4-(2-(3-(...)
Affinity DataIC50:  8.50E+3nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186433(4-methoxyphenyl 2-(3-(4-hydroxyphenyl)-4,5-dihydro...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186424(CHEMBL377038 | US8618147, 2 | phenyl 2-(3-(4-hydro...)
Affinity DataIC50:  1.00E+4nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186432(4-tert-butylphenyl 2-(3-(4-hydroxyphenyl)-4,5-dihy...)
Affinity DataIC50:  1.00E+4nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50113775(2-[(4-Hydroxy-benzylidene)-amino]-3-(4-hydroxy-phe...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186424(CHEMBL377038 | US8618147, 2 | phenyl 2-(3-(4-hydro...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186432(4-tert-butylphenyl 2-(3-(4-hydroxyphenyl)-4,5-dihy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50209087(CHEMBL221786 | benzyl-2-(4-hydroxybenzylidene)hydr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  1.10E+4nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50373158(CHEMBL402006)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of MIF-mediated dopachrome tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186442(CHEMBL208658 | US8618147, 10 | ethyl 2-(3-(4-hydro...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186442(CHEMBL208658 | US8618147, 10 | ethyl 2-(3-(4-hydro...)
Affinity DataIC50:  1.20E+4nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
The New York School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50186436((S)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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