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Found 113 with Last Name = 'aldous' and Initial = 's'
TargetKallikrein-1(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50379838(CHEMBL2011750)
Affinity DataKi:  31nMAssay Description:Inhibition of human kallikrein 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50379837(CHEMBL2011749)
Affinity DataKi:  810nMAssay Description:Inhibition of human kallikrein 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstate-specific antigen(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50379839(CHEMBL2011751)
Affinity DataIC50:  226nMAssay Description:Inhibition of human kallikrein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50092336(3-{2-[(4-Aminomethyl-cyclohexanecarbonyl)-amino]-3...)
Affinity DataIC50:  710nMAssay Description:Inhibition of plasma kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386418(CHEMBL2047313)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386416(CHEMBL2047314)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080493(5-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataIC50:  7.75E+3nMAssay Description:Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386417(CHEMBL2047315)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363300(CHEMBL1944897)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of Coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM13279(4-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080492(5-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363298(CHEMBL1944726)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363299(CHEMBL1944727)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363298(CHEMBL1944726)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363299(CHEMBL1944727)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363300(CHEMBL1944897)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363300(CHEMBL1944897)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363299(CHEMBL1944727)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363298(CHEMBL1944726)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286484(2-Cyclohexyl-5-cyclopropyl-7-(2,6-dimethyl-pyridin...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286474(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286486(5-Cyclopropyl-2-(2-dimethylamino-ethyl)-7-(2,6-dim...)
Affinity DataEC50:  930nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataEC50: >7.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286489(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286490(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286492(2-(4-Amino-cyclohexyl)-5-cyclopropyl-7-(2,6-dimeth...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286491(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286496(2-(4-Amino-cyclohexyl)-5-cyclopropyl-7-(2,6-dimeth...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286488(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286497(CHEMBL337180 | N-{4-[5-Cyclopropyl-7-(2,6-dimethyl...)
Affinity DataEC50: >5.10E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50045698(1-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.40E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286495(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286493(CHEMBL334386 | [5-Cyclopropyl-7-(2,6-dimethyl-pyri...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286494(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286499(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286498(CHEMBL130332 | N-{4-[5-Cyclopropyl-7-(2,6-dimethyl...)
Affinity DataEC50: >5.20E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286501(5-Cyclopropyl-2-(3-dimethylamino-propyl)-7-(2,6-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286500(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286485(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286487(CHEMBL133784 | [5-Cyclopropyl-7-(2,6-dimethyl-pyri...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50045706(1-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.50E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286474(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  2.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286484(2-Cyclohexyl-5-cyclopropyl-7-(2,6-dimethyl-pyridin...)
Affinity DataEC50:  900nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286494(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286499(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  5.90E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286485(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286491(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  3.20E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataEC50:  720nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286489(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  3.10E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
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