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Found 38 with Last Name = 'alharthy' and Initial = 'rd'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  32nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167896(3-(3′-Nitrophenyl)pyrido[2,3-b]pyrazine (6n))
Affinity DataIC50:  466nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167885(3-(3′-Methylphenyl)pyrido[2,3-b]pyrazine (6c...)
Affinity DataIC50:  583nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167888(3-(3′-Fluorophenyl)pyrido[2,3-b]pyrazine (6f...)
Affinity DataIC50:  899nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167890(3-(3′-Chlorophenyl)pyrido[2,3-b]pyrazine (6h...)
Affinity DataIC50:  1.26E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167896(3-(3′-Nitrophenyl)pyrido[2,3-b]pyrazine (6n))
Affinity DataIC50:  1.89E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167895(3-(4′-Nitrophenyl)pyrido[2,3-b]pyrazine (6m))
Affinity DataIC50:  1.97E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167887(3-(4′-Fluorophenyl)pyrido[2,3-b]pyrazine (6e...)
Affinity DataIC50:  2.45E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167891(3-(2′-Chlorophenyl)pyrido[2,3-b]pyrazine (6i...)
Affinity DataIC50:  2.52E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167889(3-(4′-Chlorophenyl)pyrido[2,3-b]pyrazine (6g...)
Affinity DataIC50:  2.59E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167889(3-(4′-Chlorophenyl)pyrido[2,3-b]pyrazine (6g...)
Affinity DataIC50:  2.63E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167897(3-(2′-Nitrophenyl)pyrido[2,3-b]pyrazine (6o))
Affinity DataIC50:  3.00E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167884(3-(4′-Methylphenyl)pyrido[2,3-b]pyrazine (6b...)
Affinity DataIC50:  3.06E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167892(3-(3′-Bromophenyl)pyrido[2,3-b]pyrazine (6j))
Affinity DataIC50:  3.12E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167898(3-(4′-(Piperidin-1-yl)phenyl)pyrido[2,3-b]py...)
Affinity DataIC50:  3.91E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167893(3-(2′-Bromophenyl)pyrido[2,3-b]pyrazine (6k))
Affinity DataIC50:  4.03E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167894(3-(4′-Iodophenyl)pyrido[2,3-b]pyrazine (6l))
Affinity DataIC50:  4.05E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167898(3-(4′-(Piperidin-1-yl)phenyl)pyrido[2,3-b]py...)
Affinity DataIC50:  4.75E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167886(3-(2′-Methylphenyl)pyrido[2,3-b]pyrazine (6d...)
Affinity DataIC50:  5.39E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167899(6,7,8,9-tetrahydropyrido[2,3-b]quinoxaline (6q))
Affinity DataIC50:  5.78E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167885(3-(3′-Methylphenyl)pyrido[2,3-b]pyrazine (6c...)
Affinity DataIC50:  5.88E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  6.41E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167884(3-(4′-Methylphenyl)pyrido[2,3-b]pyrazine (6b...)
Affinity DataIC50:  6.44E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167893(3-(2′-Bromophenyl)pyrido[2,3-b]pyrazine (6k))
Affinity DataIC50:  7.45E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM167883(3-Phenylpyrido[2,3-b]pyrazine (6a))
Affinity DataIC50:  9.65E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167891(3-(2′-Chlorophenyl)pyrido[2,3-b]pyrazine (6i...)
Affinity DataIC50:  9.67E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167899(6,7,8,9-tetrahydropyrido[2,3-b]quinoxaline (6q))
Affinity DataIC50:  1.09E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167887(3-(4′-Fluorophenyl)pyrido[2,3-b]pyrazine (6e...)
Affinity DataIC50:  1.12E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167892(3-(3′-Bromophenyl)pyrido[2,3-b]pyrazine (6j))
Affinity DataIC50:  1.15E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167890(3-(3′-Chlorophenyl)pyrido[2,3-b]pyrazine (6h...)
Affinity DataIC50:  1.21E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167895(3-(4′-Nitrophenyl)pyrido[2,3-b]pyrazine (6m))
Affinity DataIC50:  2.08E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167886(3-(2′-Methylphenyl)pyrido[2,3-b]pyrazine (6d...)
Affinity DataIC50:  2.12E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  2.22E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167897(3-(2′-Nitrophenyl)pyrido[2,3-b]pyrazine (6o))
Affinity DataIC50:  2.23E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167894(3-(4′-Iodophenyl)pyrido[2,3-b]pyrazine (6l))
Affinity DataIC50:  3.12E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167883(3-Phenylpyrido[2,3-b]pyrazine (6a))
Affinity DataIC50:  3.54E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  4.96E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM167888(3-(3′-Fluorophenyl)pyrido[2,3-b]pyrazine (6f...)
Affinity DataIC50:  7.98E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed