Compile Data Set for Download or QSAR
maximum 50k data
Found 21 with Last Name = 'ali' and Initial = 'ms'
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of Yaounde

Curated by ChEMBL
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

LigandPNGBDBM93134(PDE5 Inhibitor, 5 | PDE5 Inhibitor, 8)
Affinity DataIC50:  360nMAssay Description:PDE activity was measured using a modification of the IMAP fluorescence polarization phosphodiesterase assay from Molecular Devices. The assay was m...More data for this Ligand-Target Pair
In DepthDetails
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

LigandPNGBDBM93134(PDE5 Inhibitor, 5 | PDE5 Inhibitor, 8)
Affinity DataIC50:  360nMAssay Description:PDE activity was measured using a modification of the IMAP fluorescence polarization phosphodiesterase assay from Molecular Devices. The assay was m...More data for this Ligand-Target Pair
In DepthDetails
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

LigandPNGBDBM93140(PDE5 Inhibitor, 12)
Affinity DataIC50:  550nMAssay Description:PDE activity was measured using a modification of the IMAP fluorescence polarization phosphodiesterase assay from Molecular Devices. The assay was m...More data for this Ligand-Target Pair
In DepthDetails
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

LigandPNGBDBM93141(PDE5 Inhibitor, 19)
Affinity DataIC50:  560nMAssay Description:PDE activity was measured using a modification of the IMAP fluorescence polarization phosphodiesterase assay from Molecular Devices. The assay was m...More data for this Ligand-Target Pair
In DepthDetails
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

LigandPNGBDBM93136(PDE5 Inhibitor, 6)
Affinity DataIC50:  720nMAssay Description:PDE activity was measured using a modification of the IMAP fluorescence polarization phosphodiesterase assay from Molecular Devices. The assay was m...More data for this Ligand-Target Pair
In DepthDetails
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center

LigandPNGBDBM50239965(Bromhexine | CHEBI:77032)
Affinity DataIC50:  750nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center

LigandPNGBDBM420291(0591-5329 | 4-(Methoxycarbonyl)phenyl thiophene-2-...)
Affinity DataIC50:  930nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center

LigandPNGBDBM50022172((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid meth...)
Affinity DataIC50:  1.37E+3nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
Csir-Indian Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization measured at 1 min interval for 1 hr by fluorescence plate reader assayMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
Csir-Indian Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50536788(CHEMBL4537424)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization measured at 1 min interval for 1 hr by fluorescence plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
Csir-Indian Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50536789(CHEMBL4549647)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization measured at 1 min interval for 1 hr by fluorescence plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

LigandPNGBDBM93137(PDE5 Inhibitor, 9)
Affinity DataIC50:  2.40E+3nMAssay Description:PDE activity was measured using a modification of the IMAP fluorescence polarization phosphodiesterase assay from Molecular Devices. The assay was m...More data for this Ligand-Target Pair
In DepthDetails
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

LigandPNGBDBM93135(PDE5 Inhibitor, 1)
Affinity DataIC50:  2.50E+3nMAssay Description:PDE activity was measured using a modification of the IMAP fluorescence polarization phosphodiesterase assay from Molecular Devices. The assay was m...More data for this Ligand-Target Pair
In DepthDetails
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center

LigandPNGBDBM420294(8008-1235 | N-[4-(4-chlorophenyl)-3-ethyl-1,3-thia...)
Affinity DataIC50:  2.64E+3nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center

LigandPNGBDBM420292(4401-0077 | Antidepressant agent 1)
Affinity DataIC50:  2.68E+3nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

LigandPNGBDBM93138(PDE5 Inhibitor, 4)
Affinity DataIC50:  6.40E+3nMAssay Description:PDE activity was measured using a modification of the IMAP fluorescence polarization phosphodiesterase assay from Molecular Devices. The assay was m...More data for this Ligand-Target Pair
In DepthDetails
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of Yaounde

Curated by ChEMBL
LigandPNGBDBM50349974(CHEMBL1812485)
Affinity DataIC50:  7.69E+3nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of Yaounde

Curated by ChEMBL
LigandPNGBDBM50240896(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H...)
Affinity DataIC50:  3.52E+4nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of Yaounde

Curated by ChEMBL
LigandPNGBDBM50349976(ISOWIGHTEONE)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-ACP reductase(Plasmodium falciparum)
University Of Yaounde

Curated by ChEMBL
LigandPNGBDBM50349975(CHEMBL1812593)
Affinity DataIC50:  2.48E+5nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed