Affinity DataIC50: 6.70nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissueMore data for this Ligand-Target Pair