TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 1.95E+3nMAssay Description:Inhibition of Electrophorus electricus AchE assessed as inhibition constantMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 3.56E+3nMAssay Description:Inhibition of Electrophorus electricus AchE assessed as inhibition constantMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 3.81E+3nMAssay Description:Inhibition of Electrophorus electricus AchE assessed as inhibition constantMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma ligand binding domain expressed in Escherichia coli BL21 after 12 hrs by liquid scintillation ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataKi: 6.24E+3nMAssay Description:Inhibition of Electrophorus electricus AchE assessed as inhibition constantMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 7.30E+3nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma ligand binding domain expressed in Escherichia coli BL21 after 12 hrs by liquid scintillation ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 4.30E+4nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma ligand binding domain expressed in Escherichia coli BL21 after 12 hrs by liquid scintillation ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 4.36E+4nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma ligand binding domain expressed in Escherichia coli BL21 after 12 hrs by liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant caspase 3 assessed as fluorescent 7-amido-4-methylcoumarin releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of papaya papain using Z-Leu-Leu-Arg-AMC as substrate after 30 mins by spectrofluorometryMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Universidade Federal Do Piau£
Curated by ChEMBL
Universidade Federal Do Piau£
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Wistar rat plasma angiotensin 1-converting enzyme using H-hippuryl-His-Leu-OH as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of papaya papain using Z-Leu-Leu-Arg-AMC as substrate after 30 mins by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Affinity DataIC50: 59.1nMAssay Description:Inhibition of human recombinant caspase 7 assessed as fluorescent 7-amido-4-methylcoumarin releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of proteinase 3 using N-MeOSuc-Ala-Ala-Pro-Val-p-nitroanilide as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of secretory PLA2 activity in porcine pancreas using [3H]-oleate labelled membranes at a concentration of 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human kallikrein using H-Pro-Phe-Arg-AMC acetate salt as substrate measured for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of cathepsin G using Suc-Ala-Ala-Pro-Phe-p-nitroanilide as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human neutrophil elastase using chromogenic substrate (N-MeOSuc-Ala-Ala-Pro-Val-p-nitroanilide after 120 minsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of secretory PLA2 activity in porcine pancreas using [3H]-oleate labelled membranes at a concentration of 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of secretory PLA2 activity in human recombinant synovial enzyme using [3H]-oleate labelled membranes at a concentration of 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate preincubated for 10 mins followed by substrate addition by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of proteinase 3 using N-MeOSuc-Ala-Ala-Pro-Val-p-nitroanilide as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.19E+3nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Universidade Federal Do Piau£
Curated by ChEMBL
Universidade Federal Do Piau£
Curated by ChEMBL
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of Wistar rat plasma angiotensin 1-converting enzyme using H-hippuryl-His-Leu-OH as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of secretory PLA2 activity in human recombinant synovial enzyme using [3H]-oleate labelled membranes at a concentration of 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human proteinase 3 using N-MeOSuc-Ala-Ala-Pro-Val-p-nitroanilide as substrate measured for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of secretory PLA2 activity in Naja naja venom enzyme using [3H]-oleate labelled membranes at a concentration of 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of secretory PLA2 activity in Naja naja venom enzyme using [3H]-oleate labelled membranes at a concentration of 10 uMMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Federal University Of Alfenas
Curated by ChEMBL
Federal University Of Alfenas
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of secretory PLA2 activity in bee venom enzyme using [3H]-oleate labelled membranes at a concentration of 10 uMMore data for this Ligand-Target Pair