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Found 89 with Last Name = 'ambreen' and Initial = 'n'
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246417(US9447057, 1)
Affinity DataKi:  3.82E+3nM IC50:  2.80E+3nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246422(US9447057, 8)
Affinity DataKi:  7.89E+3nM IC50:  8.13E+3nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246420(US9447057, 6)
Affinity DataKi:  8.22E+3nM IC50:  8.80E+3nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246418(US9447057, 4)
Affinity DataKi:  9.23E+3nM IC50:  1.12E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246442(US9447057, 2)
Affinity DataKi:  9.60E+3nM IC50:  8.56E+3nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246443(US9447057, 3)
Affinity DataKi:  9.70E+3nM IC50:  7.90E+3nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246421(US9447057, 7)
Affinity DataKi:  1.19E+4nM IC50:  9.33E+3nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246423(US9447057, 9)
Affinity DataKi:  1.24E+4nM IC50:  1.45E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246419(US9447057, 5)
Affinity DataKi:  1.36E+4nM IC50:  7.60E+3nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246424(US9447057, 10)
Affinity DataKi:  1.48E+4nM IC50:  1.78E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM50229993(2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...)
Affinity DataKi:  2.00E+4nM IC50:  2.10E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50304608(5,5'-(propane-1,3-diyl)bis(1,3,4-oxadiazole-2(3H)-...)
Affinity DataKi:  1.50E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50304607(5-(3-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...)
Affinity DataKi:  3.60E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50304609(5-[4-t-Butyldimethylsilyloxy phenyl]-1,3,4-oxadiaz...)
Affinity DataKi:  3.60E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50304605(5-(4-hydroxyphenyl)-1,3,4-thiadiazole-2(3H)-thione...)
Affinity DataKi:  8.50E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50304606(5-(4-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...)
Affinity DataKi:  8.50E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Escherichia coli)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  670nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008884(CHEMBL3237329)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50218211(1'-(4-Methyl-benzyl)-[1,4']bipiperidinyl | CHEMBL3...)
Affinity DataIC50:  1.72E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008901(CHEMBL2430239)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008904(CHEMBL3237336)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008903(CHEMBL3237335)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50198715((2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1(4H)-yl)pr...)
Affinity DataIC50:  3.68E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008905(CHEMBL3237340)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50218209(CHEMBL250773 | Tyrosinase Inhibitor, 3 | naphthale...)
Affinity DataIC50:  6.64E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246431(US9447057, 18)
Affinity DataIC50:  6.96E+3nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM85773(Tyrosinase Inhibitor, 8)
Affinity DataIC50:  8.76E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246441(US9447057, 28)
Affinity DataIC50:  1.05E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246437(US9447057, 24)
Affinity DataIC50:  1.13E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246429(US9447057, 16)
Affinity DataIC50:  1.24E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246433(US9447057, 20)
Affinity DataIC50:  1.30E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.67E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246432(US9447057, 19)
Affinity DataIC50:  1.68E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246435(US9447057, 22)
Affinity DataIC50:  1.79E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50218210(2,2,2-trifluoro-1-(4-(piperidin-1-yl)piperidin-1-y...)
Affinity DataIC50:  1.81E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008885(CHEMBL3237330)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246439(US9447057, 26)
Affinity DataIC50:  1.90E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThymidine phosphorylase(Escherichia coli)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50479924(CHEMBL489635)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Escherichia coli)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50131078(3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehy...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM85774(Tyrosinase Inhibitor, 10)
Affinity DataIC50:  1.95E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246436(US9447057, 23)
Affinity DataIC50:  1.96E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThymidine phosphorylase(Escherichia coli)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50479927(CHEMBL491260)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008906(CHEMBL3237343)
Affinity DataIC50:  1.99E+4nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246426(US9447057, 12)
Affinity DataIC50:  2.02E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246428(US9447057, 14)
Affinity DataIC50:  2.04E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
TBA

US Patent
LigandPNGBDBM246444(US9447057, 15)
Affinity DataIC50:  2.04E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008887(CHEMBL3237332)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50008902(CHEMBL3237334)
Affinity DataIC50:  2.15E+4nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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