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Found 260 with Last Name = 'andersson' and Initial = 'c'
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50232153((1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethox...)
Affinity DataKi:  0.0300nM ΔG°:  -55.8kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139371(eplivanserin)
Affinity DataKi:  0.0460nM ΔG°:  -54.8kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.0830nM ΔG°:  -53.5kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.440nM ΔG°:  -49.6kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Nuplazid | Pimavanserin | Pimavanserin h...)
Affinity DataKi:  0.5nM ΔG°:  -49.3kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  0.550nM ΔG°:  -49.1kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139371(eplivanserin)
Affinity DataKi:  1.30nM ΔG°:  -47.1kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  1.30nM ΔG°:  -47.1kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Nuplazid | Pimavanserin | Pimavanserin h...)
Affinity DataKi:  1.60nM ΔG°:  -46.7kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  1.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM86496(AC-90179 | N-(4-Methylbenzyl)-N-(1-methyl-4-piperi...)
Affinity DataKi:  2.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50232153((1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethox...)
Affinity DataKi:  3.80nM ΔG°:  -44.7kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50093777(CHEMBL81377 | N-Cyclooctyl-N-{1-[3-(4-fluoro-pheno...)
Affinity DataKi:  20nMAssay Description:Compound was evaluated for its binding against 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  49.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  70.2nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamine synthetase(Glycine max)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50260541(CHEMBL452711 | L-2-Amino-4-hydroxyaminobutyric aci...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of soybean glutamine synthetase by transferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamine synthetase(Salmonella typhimurium)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50260535((2S,5R)-2,6-diamino-5-hydroxyhexanoic acid | (2S,5...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of Salmonella typhimurium glutamine synthetase by transferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataIC50:  0.0690nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataIC50:  0.316nMAssay Description:Compound was evaluated for its inverse agonist activity against 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139371(eplivanserin)
Affinity DataIC50:  1nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048422(CHEMBL3315084)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50232153((1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethox...)
Affinity DataIC50:  1.10nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Nuplazid | Pimavanserin | Pimavanserin h...)
Affinity DataIC50:  1.90nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048421(CHEMBL3315083)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataIC50:  3nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataIC50:  4.5nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048447(CHEMBL3315089)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048446(CHEMBL3315088)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048476(CHEMBL3315079)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048477(CHEMBL3315080)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048463(CHEMBL3315072)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048443(CHEMBL3315087)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataIC50:  13nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50093777(CHEMBL81377 | N-Cyclooctyl-N-{1-[3-(4-fluoro-pheno...)
Affinity DataIC50:  13nMAssay Description:Compound was evaluated for its inverse agonist activity against 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048474(CHEMBL3315077)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048424(CHEMBL3315086)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50041866(CHEMBL48017 | N-(3,5-Dichloro-pyridin-4-yl)-3,4-di...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048478(CHEMBL3315081)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048455(CHEMBL3315090)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048475(CHEMBL3315078)
Affinity DataIC50:  45nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048423(CHEMBL3315085)
Affinity DataIC50:  61nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50:  63nMAssay Description:In vitro inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048473(CHEMBL3315076)
Affinity DataIC50:  63nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM50451131(AC-165043 | CHEMBL80093)
Affinity DataIC50:  79nMAssay Description:Compound was evaluated for its inverse agonist activity against 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50048470(CHEMBL3313943)
Affinity DataIC50:  81nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Ume£

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  82nMAssay Description:Inhibition of mouse AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Nuplazid | Pimavanserin | Pimavanserin h...)
Affinity DataIC50:  91nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataIC50:  100nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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