Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortex membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: >19nMAssay Description:Inhibition of [3H]ketanserin binding to 5HT2A receptor in rat cortex membrane at 30 uMMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 1.15E+3nMAssay Description:Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 2.49E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 5.87E+3nMAssay Description:Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 6.45E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 6.82E+3nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 8.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 8.22E+3nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 8.44E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 1.23E+4nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
Affinity DataIC50: 289nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
Affinity DataIC50: 388nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
Affinity DataIC50: 599nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
Affinity DataIC50: 853nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataIC50: 7.08E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataIC50: 7.08E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair