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Found 409 with Last Name = 'andrews' and Initial = 'ps'
LigandPNGBDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of mTOR assessed as inhibition of phosphorylation of 4EBP1 by Lantha-Screen enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396260(CHEMBL2172324)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396243(CHEMBL2172308 | US10370379, Compound TSR-011)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396240(CHEMBL2172311)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396274(CHEMBL2172314)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396263(CHEMBL2172315)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396273(CHEMBL2172316)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396272(CHEMBL2172317)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396264(CHEMBL2172304)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396268(CHEMBL2172321)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396248(CHEMBL2172335)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396245(CHEMBL2172306)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396239(CHEMBL2172312)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396250(CHEMBL2172333)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396240(CHEMBL2172311)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of ALK Tyr1604 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396254(CHEMBL2172330)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396241(CHEMBL2172310)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396256(CHEMBL2172328)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396253(CHEMBL2172331)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396270(CHEMBL2172319)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396275(CHEMBL2172313)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396259(CHEMBL2172325)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396244(CHEMBL2172307)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396246(CHEMBL2172305)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396249(CHEMBL2172334)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396266(CHEMBL2172302)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396298(CHEMBL2172489)
Affinity DataIC50:  2nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396302(CHEMBL2172485)
Affinity DataIC50:  2nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396305(CHEMBL2172482)
Affinity DataIC50:  2nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50341035(1-(4-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-b...)
Affinity DataIC50:  2nMAssay Description:Inhibition of mTOR assessed as inhibition of phosphorylation of 4EBP1 by Lantha-Screen enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396239(CHEMBL2172312)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK Tyr1604 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396252(CHEMBL2172332)
Affinity DataIC50:  2nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396242(CHEMBL2172309)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396322(CHEMBL2172629)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50341054(3-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396261(CHEMBL2172323)
Affinity DataIC50:  3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396267(CHEMBL2172301)
Affinity DataIC50:  3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396269(CHEMBL2172320)
Affinity DataIC50:  3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396316(CHEMBL2172635)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396265(CHEMBL2172303)
Affinity DataIC50:  3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396297(CHEMBL2172490)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396301(CHEMBL2172486)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396307(CHEMBL2172480)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396308(CHEMBL2172636)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396247(CHEMBL2172336)
Affinity DataIC50:  3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396303(CHEMBL2172484)
Affinity DataIC50:  4nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50341054(3-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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