TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition constant incubated for 10 mins by phenol red dye based stopped-flow CO2 h...More data for this Ligand-Target Pair
Affinity DataKi: 0.0440nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...More data for this Ligand-Target Pair
Affinity DataKi: 0.0870nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 assessed as inhibition constant incubated for 10 mins by phenol red dye based stopped-flow CO2 ...More data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Inhibition of MMP9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.263nMAssay Description:Inhibition of human CA12 incubated for 15 mins by stopped- flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.290nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetPlasma kallikrein(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl
Curated by ChEMBL
Ecole Polytechnique F�D�Rale De Lausanne Epfl
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of human recombinant polyhistidine-tagged plasma kallikrein expressed in Escherichia coli XL1 blue using Z-FR-AMC as substrate by fluorime...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.410nMAssay Description:Inhibition of human recombinant CA2 preincubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.410nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.420nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.440nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.440nMAssay Description:Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-7 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Inhibition of human recombinant CA2 preincubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 preincubated for 10 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant full length human carbonic anhydrase-2 assessed as reduction in CO2 hydration after 15 mins by phenol red dye based stopped...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Department Of Chemical Sciences National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataKi: 0.510nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair