Affinity DataKi: 440nMAssay Description:Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione ...More data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione ...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione ...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione ...More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+3nMAssay Description:Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione ...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione ...More data for this Ligand-Target Pair
Affinity DataKi: 6.70E+3nMAssay Description:Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione ...More data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione ...More data for this Ligand-Target Pair
Affinity DataKi: 9.60E+3nMAssay Description:Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione ...More data for this Ligand-Target Pair
Affinity DataKi: 9.90E+3nMAssay Description:Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione ...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of 26-mer BIMBH3 peptide from GST-tagged Bcl-Xl (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataIC50: 1.5nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of 26-mer BIMBH3 peptide from GST-tagged Bcl-Xl (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assayMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataIC50: 6.20nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Displacement of 26-mer BIMBH3 peptide from GST-tagged Bcl-Xl (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataIC50: 7.10nM Kd: 1.40nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assayMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of 20S proteasome activity in human ANBL-6 cellsMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Cancer Therapeutics Crc
Curated by ChEMBL
Cancer Therapeutics Crc
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataIC50: 13nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair