TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Glaxosmithkline R&D
Curated by ChEMBL
Glaxosmithkline R&D
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of human partial length TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Glaxosmithkline R&D
Curated by ChEMBL
Glaxosmithkline R&D
Curated by ChEMBL
Affinity DataKi: 0.398nMAssay Description:Inhibition of human partial length TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Glaxosmithkline R&D
Curated by ChEMBL
Glaxosmithkline R&D
Curated by ChEMBL
Affinity DataKi: 0.794nMAssay Description:Inhibition of human partial length TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Glaxosmithkline R&D
Curated by ChEMBL
Glaxosmithkline R&D
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human partial length TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Binding affinity to human partial length PCAF bromodomain expressed in mammalian expression system by BROMOscan methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Binding affinity to human partial length GCN5 expressed in bacterial expression system by BROMOscan methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity to human partial length GCN5 expressed in bacterial expression system by BROMOscan methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity to human partial length PCAF bromodomain expressed in mammalian expression system by BROMOscan methodMore data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Glaxosmithkline R&D
Curated by ChEMBL
Glaxosmithkline R&D
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of human partial length TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human partial length BRD9 (R130 to V259 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
Affinity DataKi: 3.98nMAssay Description:Inhibition of GST-tagged p38alpha by fluorescence polarization methodMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant p38alpha-mediated ATF2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant p38alpha-mediated ATF2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Inhibition of GST-tagged p38alpha by fluorescence polarization methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair